{"id":"W2062794706","doi":"10.1016/s0014-5793(02)02494-8","title":"Lamellipodial localization of <i>Dictyostelium</i> myosin heavy chain kinase A is mediated via F‐actin binding by the coiled‐coil domain","year":2002,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; American Cancer Society","keywords":"Myosin; Dictyostelium; Coiled coil; Actin; Dictyostelium discoideum; Myosin light-chain kinase; Cell biology; Pseudopodia; Actin-binding protein; Biology; Actin remodeling; Chemotaxis; Cytoskeleton; Actin cytoskeleton; Biochemistry; Receptor; Cell; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001783838,0.0001677435,0.0001454643,0.00004991268,0.0001384122,0.00003004411,0.0001890736,0.0001252271,0.000241546],"category_scores_gemma":[0.00004011141,0.0001433824,0.0001231309,0.0001833655,0.00007578116,0.000007301486,0.00005980815,0.0001385026,0.00005483543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002572808,"about_ca_system_score_gemma":0.00001044296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008130055,"about_ca_topic_score_gemma":0.00003040626,"domain_scores_codex":[0.9988847,0.0001109947,0.0002802466,0.0002885259,0.0001881503,0.0002473919],"domain_scores_gemma":[0.9993603,0.0000314808,0.0001625162,0.0003337053,0.00004729565,0.00006471763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003658006,0.00007048298,0.00005422304,0.000008372347,0.00004465757,0.000003375799,0.0002287716,0.0000396832,0.9054969,0.00001118781,0.0928679,0.001137876],"study_design_scores_gemma":[0.0004962742,0.0001212034,0.000003168011,0.00001796414,0.00002313936,0.00001659964,0.0001067012,0.00358498,0.7158183,0.000008118132,0.2796348,0.0001686924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9438076,0.0009194351,0.04419489,0.009411626,0.0005759859,0.000322198,0.0001868618,0.00001876979,0.000562648],"genre_scores_gemma":[0.9907704,0.0002751244,0.0001047241,0.007755015,0.000234909,0.00002153766,0.0004335225,0.00003439464,0.0003703788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1896786,"threshold_uncertainty_score":0.5846964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007265394935507049,"score_gpt":0.1992382067699946,"score_spread":0.1919728118344876,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}