{"id":"W2062862673","doi":"10.1007/bf03256387","title":"Predictive Value of the Lymphocyte Toxicity Assay in the Diagnosis of Drug Hypersensitivity Syndrome","year":2010,"lang":"en","type":"article","venue":"Molecular Diagnosis & Therapy","topic":"Drug-Induced Adverse Reactions","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's Hospital of Western Ontario; Health Sciences Centre; Sunnybrook Health Science Centre; Western University","funders":"","keywords":"Gold standard (test); Medicine; False positive paradox; Predictive value; Positive predicative value; Drug; Predictive value of tests; False Negative Reactions; Medical record; Internal medicine; Immunology; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001009553,0.000264517,0.0005223477,0.0001653303,0.00009043979,0.00001295685,0.0003705595,0.0001723758,0.00001908249],"category_scores_gemma":[0.0005379913,0.0001664792,0.0004341863,0.0007666949,0.000347223,0.00009810013,0.00007325118,0.0005848316,0.000006864906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000127578,"about_ca_system_score_gemma":0.0002233392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008976677,"about_ca_topic_score_gemma":0.0001918862,"domain_scores_codex":[0.9975826,0.0006160383,0.0004115253,0.0003625952,0.0007126216,0.0003146453],"domain_scores_gemma":[0.997382,0.001021322,0.0002577122,0.001091558,0.0001598121,0.00008762484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001340511,0.006612044,0.3128368,0.00009952695,0.0009295429,0.0004381386,0.007515665,0.0005048231,0.6153341,0.001834361,0.0002158021,0.05354519],"study_design_scores_gemma":[0.001446882,0.00007753928,0.579169,0.0001486504,0.000133105,0.0001221862,0.0004943772,0.0001086715,0.4162162,0.0001826534,0.001772904,0.0001278942],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919283,0.0003218947,0.00003682386,0.003440166,0.0003350037,0.001261075,0.00005501021,0.00003009775,0.002591643],"genre_scores_gemma":[0.9973577,0.0007086031,0.0001306696,0.001276414,0.0000421839,0.0004206742,0.000006930042,0.00004129338,0.00001555278],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2663322,"threshold_uncertainty_score":0.6788824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0115931523824743,"score_gpt":0.2577031673155644,"score_spread":0.2461100149330901,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}