{"id":"W2062924614","doi":"10.1161/circulationaha.109.865956","title":"Survival and Cardiac Remodeling After Myocardial Infarction Are Critically Dependent on the Host Innate Immune Interleukin-1 Receptor-Associated Kinase-4 Signaling","year":2009,"lang":"en","type":"article","venue":"Circulation","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Medicine; Innate immune system; Myocardial infarction; Interleukin 33; Receptor; Signal transduction; Immune system; Inflammation; Immunology; Interleukin; Cardiology; Cytokine; Internal medicine; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002352255,0.0005529547,0.0002958629,0.0002199748,0.000173252,0.0002970403,0.0001807454,0.0002699075,0.001576714],"category_scores_gemma":[0.0002050016,0.0001303506,0.0001925592,0.00009168343,0.0003771941,0.0002355177,0.0004047536,0.0005746054,0.0003914624],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001814396,"about_ca_system_score_gemma":0.0002681485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000943994,"about_ca_topic_score_gemma":0.0001442559,"domain_scores_codex":[0.9998447,0.0000314201,0.00001277043,0.00002452992,0.00003190512,0.00005467088],"domain_scores_gemma":[0.9997608,0.0000163171,0.0001256049,0.00001642216,0.0000199991,0.00006077906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002740561,0.0003181434,0.01009531,0.0002336298,0.00004955765,0.0005295871,0.00005793368,0.0001734776,0.9675716,0.000348547,0.0003828301,0.01749879],"study_design_scores_gemma":[0.0007674976,0.00746344,0.6425681,0.0001883615,0.0005279637,0.004743094,0.0004199674,0.00233507,0.3275052,0.002117666,0.01130319,0.00006043608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901711,0.00684042,0.001125521,0.0002248836,0.00006302005,0.00003252631,0.0001464079,0.00006900072,0.001327025],"genre_scores_gemma":[0.9932734,0.003232256,0.0007742192,0.0001266371,0.00008702584,0.0001002757,0.0003595552,0.00001236792,0.002034205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001576714,"threshold_uncertainty_score":0.005274653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02113635140120286,"score_gpt":0.2585261729558828,"score_spread":0.23738982155468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}