{"id":"W2062955637","doi":"10.1016/j.humimm.2015.02.002","title":"ER egress of invariant chain isoform p35 requires direct binding to MHCII molecules and is inhibited by the NleA virulence factor of enterohaemorrhagic Escherichia coli","year":2015,"lang":"en","type":"article","venue":"Human Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Université de Montréal","funders":"","keywords":"Gene isoform; Escherichia coli; Virulence factor; Chemistry; Cell biology; Virulence; Transcription factor; Biology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001661487,0.0002546672,0.0001879613,0.0001728978,0.0001727777,0.000454256,0.0002339553,0.0002634384,0.001120441],"category_scores_gemma":[0.0002146019,0.00017104,0.0002650571,0.0001056221,0.0002128677,0.0002257448,0.0002846617,0.0006042257,0.0004936391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004423148,"about_ca_system_score_gemma":0.0002003572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009385478,"about_ca_topic_score_gemma":0.001199621,"domain_scores_codex":[0.9997589,0.00003628989,0.0000156955,0.00002719473,0.00004245211,0.000119432],"domain_scores_gemma":[0.9997639,0.00005982754,0.00004778135,0.00004292604,0.00002426397,0.00006128218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001401381,0.0000207529,0.0001313847,0.000007874697,0.000001803322,0.00004353657,0.000009780806,0.00001633238,0.9991678,0.0000763438,0.00002273132,0.0003614742],"study_design_scores_gemma":[0.00002463938,0.0002008615,0.01891982,0.000007815551,0.000009674508,0.0003927984,0.00008868879,0.001293818,0.977281,0.00008772503,0.001688217,0.000004930344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977484,0.0004987795,0.0008421738,0.0000502625,0.00001286248,0.000005119851,0.00009129259,0.0000238501,0.0007272427],"genre_scores_gemma":[0.9971624,0.0001649388,0.0004603783,0.00003110716,0.000005591948,0.000005176809,0.0003497732,0.00001677481,0.001803846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001120441,"threshold_uncertainty_score":0.003748298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02839126685698309,"score_gpt":0.2570211010365425,"score_spread":0.2286298341795594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}