{"id":"W2062960628","doi":"10.1016/j.stem.2014.10.012","title":"Stem Cells to Insulin Secreting Cells: Two Steps Forward and Now a Time to Pause?","year":2014,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"Diabetes Canada; University of Alberta","funders":"","keywords":"Biology; Regenerative medicine; Embryonic stem cell; Stem cell; Insulin; Phenotype; Perspective (graphical); Type 2 diabetes; Cell biology; Cellular differentiation; In vitro; Diabetes mellitus; Bioinformatics; Endocrinology; Genetics; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01308189,0.001022337,0.002365459,0.0009340686,0.002669347,0.008832268,0.002236414,0.009757441,0.01764403],"category_scores_gemma":[0.0112879,0.0004078112,0.00152076,0.0007293021,0.01276506,0.02615352,0.005335241,0.02479446,0.005120203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002260129,"about_ca_system_score_gemma":0.006832165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00191142,"about_ca_topic_score_gemma":0.002875601,"domain_scores_codex":[0.9971108,0.0008927287,0.0002936115,0.0004056246,0.0007524358,0.0005447912],"domain_scores_gemma":[0.9862518,0.007555608,0.0006450136,0.000776433,0.002413797,0.002357358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0018567,0.0008311467,0.001916084,0.003725982,0.00021344,0.00137291,0.002954757,0.0005900279,0.008773875,0.3350514,0.3286214,0.3140923],"study_design_scores_gemma":[0.0002441285,0.000734937,0.001125968,0.002197961,0.000122819,0.001327584,0.007106157,0.0003351507,0.003468558,0.1923372,0.7907959,0.000203733],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.00253744,0.342855,0.004484541,0.6083359,0.03380757,0.0000301136,0.0000980675,0.0001600048,0.007691394],"genre_scores_gemma":[0.08748481,0.487374,0.01922576,0.3312384,0.04297084,0.0001848536,0.0003688494,0.0002547656,0.03089774],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01764403,"threshold_uncertainty_score":0.06918448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008474582966641867,"score_gpt":0.2109626172222965,"score_spread":0.2024880342556546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}