{"id":"W2063002707","doi":"10.1111/jne.12207","title":"Mutational Analysis of the Genes Encoding RFAmide‐Related Peptide‐3, the Human Orthologue of Gonadotrophin‐Inhibitory Hormone, and its Receptor (<scp>GPR</scp>147) in Patients with Gonadotrophin‐Releasing Hormone‐Dependent Pubertal Disorders","year":2014,"lang":"en","type":"article","venue":"Journal of Neuroendocrinology","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Horticultural and Herbal Science, Rural Development Administration; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Hypogonadotrophic hypogonadism; Biology; Endocrinology; Internal medicine; Gene; Genetics; Hypogonadotropic hypogonadism; Kisspeptin; Gonadotropin-releasing hormone; Hypothalamus; Hormone; Luteinizing hormone; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002291654,0.0003190054,0.001034601,0.0008223057,0.0001540004,0.00001541812,0.0003544172,0.00008553614,0.000006832868],"category_scores_gemma":[0.001152216,0.0001950468,0.0003349374,0.0006711546,0.0005156251,0.0002101782,0.0001485945,0.0008161613,0.000001012377],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009112251,"about_ca_system_score_gemma":0.0001208846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007333752,"about_ca_topic_score_gemma":0.00004736838,"domain_scores_codex":[0.9966114,0.0005770036,0.001233978,0.0004163644,0.0007237036,0.0004375709],"domain_scores_gemma":[0.9967954,0.0005310344,0.001547068,0.0004287628,0.0005903044,0.000107431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008558744,0.0008127023,0.6202055,0.00005794529,0.002541167,0.00012605,0.0008574776,0.00415962,0.3664978,0.0006155779,0.0001413956,0.003128809],"study_design_scores_gemma":[0.0043386,0.001510984,0.9906646,0.00004606903,0.001174071,0.0003541543,0.0002637023,0.000270314,0.001001708,0.0001058262,0.0001791709,0.00009078565],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955348,0.002274842,0.00002220322,0.001391135,0.0001832472,0.0004528605,0.00001987551,0.00001076445,0.00011031],"genre_scores_gemma":[0.9991264,0.0004544005,0.00009678952,0.00007940482,0.00009098185,0.000007321937,0.00001206447,0.00003761392,0.00009506114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3704591,"threshold_uncertainty_score":0.7953779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006952135223950106,"score_gpt":0.217402054458132,"score_spread":0.2104499192341819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}