{"id":"W2063030642","doi":"10.1046/j.1471-4159.2000.0752358.x","title":"Inhibition of Aberrant and Constitutive Phosphorylation of the High‐Molecular‐Mass Neurofilament Subunit by CEP‐1347 (KT7515), an Inhibitor of the Stress‐Activated Protein Kinase Signaling Pathway","year":2000,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Phosphorylation; Neurofilament; Protein subunit; Cell biology; Neurite; Kinase; Protein kinase A; Signal transduction; Chemistry; Extracellular; Biology; Molecular biology; Biochemistry; Immunology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005739696,0.0004072741,0.0002148302,0.0001094354,0.0001013026,0.0001631068,0.0001818818,0.0001529234,0.0007007572],"category_scores_gemma":[0.00007786561,0.00009495808,0.0002091061,0.0001094611,0.0001813002,0.0001485883,0.0001494057,0.0005318844,0.0001898725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002574241,"about_ca_system_score_gemma":0.0002202192,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005507098,"about_ca_topic_score_gemma":0.001150769,"domain_scores_codex":[0.9999394,0.000005185546,0.000007562452,0.00000952708,0.00001616061,0.00002214301],"domain_scores_gemma":[0.9999293,0.00001106911,0.00002064708,0.000005341667,0.000006047852,0.0000275796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008144528,0.00003009044,0.00008225396,0.00002875394,0.000004533197,0.00003712989,0.000006571464,0.00004015135,0.9988942,0.00002812382,0.00001688745,0.0007498667],"study_design_scores_gemma":[0.00001559643,0.000741493,0.007012787,0.000004100732,0.00001314931,0.0002935481,0.00001433259,0.0007159355,0.9905875,0.00002017589,0.0005777968,0.000003595309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981028,0.000551078,0.0004713757,0.00002276653,0.00001130296,0.00001410666,0.000138183,0.00002887889,0.0006595609],"genre_scores_gemma":[0.9968807,0.0007703699,0.001183495,0.00001632056,0.000004407425,0.00002946571,0.0003499732,0.00000673676,0.0007585418],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007007572,"threshold_uncertainty_score":0.00234431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006731083685808762,"score_gpt":0.2175397629407533,"score_spread":0.2108086792549445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}