{"id":"W2063030642","doi":"10.1046/j.1471-4159.2000.0752358.x","title":"Inhibition of Aberrant and Constitutive Phosphorylation of the High‐Molecular‐Mass Neurofilament Subunit by CEP‐1347 (KT7515), an Inhibitor of the Stress‐Activated Protein Kinase Signaling Pathway","year":2000,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Phosphorylation; Neurofilament; Protein subunit; Cell biology; Neurite; Kinase; Protein kinase A; Signal transduction; Chemistry; Extracellular; Biology; Molecular biology; Biochemistry; Immunology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002264351,0.0001523189,0.0002267211,0.00002455233,0.00006510344,0.000009705357,0.0002470068,0.0001663578,0.00003076534],"category_scores_gemma":[0.0001338758,0.0001028236,0.0001392343,0.0001412541,0.0004388748,0.00001016898,0.00006941314,0.0002918185,9.741003e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001288172,"about_ca_system_score_gemma":0.0001756332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001225712,"about_ca_topic_score_gemma":7.550608e-7,"domain_scores_codex":[0.9986125,0.0002357943,0.0004863915,0.0001963421,0.0003156708,0.000153357],"domain_scores_gemma":[0.9987438,0.00002438006,0.000577049,0.0002938399,0.0002894941,0.00007145266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004031064,0.0001981264,0.0009281721,0.00007732985,0.00004690511,0.00001302334,0.00005303698,0.00009804298,0.9977898,0.000006469905,0.0000345864,0.0003514058],"study_design_scores_gemma":[0.0008411465,0.0004041019,0.0009654327,0.0001834372,0.00003063218,0.00005947191,0.0001066824,0.00001234687,0.9971539,0.00004090602,0.0001126765,0.00008926568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988558,0.0005363796,0.00003625623,0.0001053925,0.00004765073,0.0002137389,0.00007690061,0.000001584819,0.000126288],"genre_scores_gemma":[0.9996806,0.00007019223,0.00004461152,0.00003427532,0.00004852509,0.000003697997,0.00002814641,0.00001312738,0.00007685781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008247576,"threshold_uncertainty_score":0.4193023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006731083685808762,"score_gpt":0.2175397629407533,"score_spread":0.2108086792549445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}