{"id":"W2063076947","doi":"10.1158/1538-7445.am10-1950","title":"Abstract 1950: Suppression of RISC-independent decoy and RISC-mediated RNA-pairing activities of microRNA-328 is required for maturation-arrest and enhanced survival of blast crisis CML progenitors","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Biology; Cancer research; CEBPA; Cell biology; Progenitor cell; microRNA; Molecular biology; Stem cell; Transcription factor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001008615,0.000271675,0.0002271997,0.0001146919,0.0001464616,0.0002100909,0.0001617482,0.0001834866,0.002892935],"category_scores_gemma":[0.00008468521,0.0001153828,0.0001693337,0.00005958447,0.0001609379,0.0000902618,0.0002148418,0.000471849,0.001091117],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002594106,"about_ca_system_score_gemma":0.0001798244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000256944,"about_ca_topic_score_gemma":0.0003881914,"domain_scores_codex":[0.9998726,0.00002085861,0.00001508056,0.00002880643,0.0000398535,0.00002276207],"domain_scores_gemma":[0.999923,0.00001134992,0.00002245902,0.00001063737,0.000006978199,0.00002555364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005545415,0.00001084274,0.00005181372,0.00001345818,0.000001304918,0.00002589492,0.000003348976,0.00001700862,0.9993342,0.00004405685,0.0000523844,0.0003903328],"study_design_scores_gemma":[0.00001138033,0.0001021812,0.001905549,0.00000324625,0.000003887687,0.000141964,0.000005696509,0.0005371455,0.9946585,0.0000225907,0.002605958,0.000001819103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886624,0.001187979,0.00468116,0.0001667683,0.00006607198,0.00007666845,0.001485769,0.0003194266,0.003353603],"genre_scores_gemma":[0.9887892,0.0002968007,0.002843453,0.00007555915,0.00001714262,0.00007154724,0.002028005,0.00005443775,0.0058239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002892935,"threshold_uncertainty_score":0.009677827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.024316116531458,"score_gpt":0.3485095511966734,"score_spread":0.3241934346652154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}