{"id":"W2063166249","doi":"10.1016/j.bbrc.2009.09.081","title":"Glucose is a key regulator of VEGFR2/KDR in human epithelial ovarian carcinoma cells","year":2009,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research; Ontario Institute for Cancer Research","keywords":"Downregulation and upregulation; Autocrine signalling; Endocrinology; Internal medicine; Angiogenesis; Vascular endothelial growth factor; Cancer research; Glucose-regulated protein; Kinase insert domain receptor; Biology; Endoplasmic reticulum; Receptor; Vascular endothelial growth factor A; Unfolded protein response; Chemistry; Cell biology; Medicine; Biochemistry; VEGF receptors","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009821547,0.0002733159,0.0002968399,0.0002514858,0.0002313782,0.0004428789,0.0002197155,0.0002042355,0.001807841],"category_scores_gemma":[0.0001308761,0.0001561928,0.0002355469,0.0004337892,0.000159679,0.000223788,0.000168134,0.0003856071,0.0003621795],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005792434,"about_ca_system_score_gemma":0.0003065846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005824277,"about_ca_topic_score_gemma":0.003536377,"domain_scores_codex":[0.9998426,0.00002750529,0.000009926582,0.00003173645,0.00003491808,0.00005329839],"domain_scores_gemma":[0.9999558,0.00001085201,0.000006771773,0.000006757664,0.00000931802,0.00001047906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005658431,0.00003607015,0.0005421277,0.00006262225,0.00001005414,0.0001457987,0.00003443243,0.00009995684,0.9964592,0.0002393006,0.000257907,0.001546604],"study_design_scores_gemma":[0.00004834246,0.0002158664,0.01930876,0.000006418164,0.00003788886,0.0002656514,0.0001602706,0.001537396,0.9717975,0.0001305882,0.006480329,0.00001110722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985803,0.006568069,0.0015031,0.0004630115,0.0001375534,0.00003009957,0.00185726,0.0001110902,0.003526826],"genre_scores_gemma":[0.9933156,0.00147002,0.0006394843,0.0001087848,0.00001454428,0.00003204314,0.001547975,0.00001714611,0.00285435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005824277,"threshold_uncertainty_score":0.01158071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0473416007960094,"score_gpt":0.3567455348016165,"score_spread":0.3094039340056071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}