{"id":"W2063211660","doi":"10.1038/mt.2014.17","title":"Enriched Protein Screening of Human Bone Marrow Mesenchymal Stromal Cell Secretions Reveals MFAP5 and PENK as Novel IL-10 Modulators","year":2014,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institute of Allergy and Infectious Diseases; National Institutes of Health; B.P. Koirala Institute of Health Sciences; Western University; National Human Genome Research Institute; National Institute of Diabetes and Digestive and Kidney Diseases; Shriners Hospitals for Children","keywords":"Stromal cell; Biology; Bone marrow; Mesenchymal stem cell; Cell; Secretory protein; In vivo; In vitro; Molecular biology; Cell culture; Cell biology; Gene; Computational biology; Cancer research; Immunology; Biochemistry; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001619016,0.0003835864,0.0002761247,0.0003104222,0.0001241941,0.0002500413,0.0001378789,0.0001655337,0.0006880643],"category_scores_gemma":[0.0001565365,0.00008065116,0.000271972,0.0002322571,0.0001143955,0.0001210903,0.0001721095,0.0002441173,0.0002574049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002097163,"about_ca_system_score_gemma":0.0002079713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005300602,"about_ca_topic_score_gemma":0.0009157233,"domain_scores_codex":[0.9998844,0.00001852375,0.00001107024,0.00002156991,0.00004208833,0.00002230686],"domain_scores_gemma":[0.999958,0.00001034213,0.000008154575,0.000003910396,0.000008186124,0.00001139315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001754211,0.00002399629,0.0008047289,0.00003162398,0.000009920755,0.00007932907,0.000007231393,0.000136591,0.9947137,0.00001956107,0.00004170608,0.003956131],"study_design_scores_gemma":[0.0000144688,0.0003167018,0.01473404,0.000006324218,0.00002425519,0.0003073786,0.00003013737,0.00166375,0.9810255,0.00003754159,0.001834782,0.000005198956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898878,0.002104968,0.004773627,0.0001710323,0.00001671436,0.00007053605,0.00172634,0.00007879204,0.001170079],"genre_scores_gemma":[0.9816518,0.001798083,0.01109376,0.0001935373,0.00001062315,0.0000654533,0.00337581,0.00002154213,0.001789417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006880643,"threshold_uncertainty_score":0.002301872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009205371349678429,"score_gpt":0.230502938022534,"score_spread":0.2212975666728556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}