{"id":"W2063213723","doi":"10.1002/pbc.22366","title":"Phase I study of valspodar (PSC‐833) with mitoxantrone and etoposide in refractory and relapsed pediatric acute leukemia: A report from the Children's Oncology Group","year":2010,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre","funders":"National Cancer Institute; National Center for Research Resources; U.S. Public Health Service","keywords":"Medicine; Mitoxantrone; Etoposide; Pediatric oncology; Oncology; Refractory (planetary science); Internal medicine; Phases of clinical research; Blood cancer; Chemotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007176343,0.0003677079,0.0008763528,0.0003321179,0.0001283018,0.00002595923,0.0002541474,0.0003447869,0.00006927717],"category_scores_gemma":[0.0003595122,0.0002421146,0.00005830476,0.0008492105,0.0002538724,0.000153921,0.0002323444,0.001534217,0.000002344665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003209965,"about_ca_system_score_gemma":0.002471223,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009570207,"about_ca_topic_score_gemma":0.003246964,"domain_scores_codex":[0.9968256,0.0001804833,0.0007819975,0.0008554906,0.0007948025,0.0005616422],"domain_scores_gemma":[0.997211,0.001004331,0.0005138254,0.00076401,0.0001868127,0.0003199613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002259359,0.003105005,0.9841266,0.00008101141,0.000547552,0.002137415,0.001842768,0.000002139954,0.002262069,0.000004836569,0.001609153,0.002022125],"study_design_scores_gemma":[0.06540988,0.007124854,0.9170775,0.00002889163,0.007364737,0.001400974,0.0005211905,0.0000721773,0.0002211498,0.00003066288,0.0003696662,0.0003782794],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927733,0.004358215,0.00001269726,0.0007094517,0.0002469873,0.001671117,0.00009448068,0.00004473106,0.00008901035],"genre_scores_gemma":[0.9908448,0.00578582,0.0005149921,0.0002021654,0.002212308,0.0002408341,0.00004184268,0.00006646065,0.00009082029],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06704903,"threshold_uncertainty_score":0.9970251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00796719678156765,"score_gpt":0.2972486884401671,"score_spread":0.2892814916585995,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}