{"id":"W2063330183","doi":"10.1111/j.0300-9475.2004.01371.x","title":"Humoral Proinflammatory Cytokine and SAA Generation Profiles and Spatio‐Temporal Relationship Between SAA and Lysosomal Cathepsin B and D in Murine Splenic Monocytoid Cells During AA Amyloidosis","year":2004,"lang":"en","type":"article","venue":"Scandinavian Journal of Immunology","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Serum amyloid A; Cathepsin B; Amyloidosis; Serum Amyloid A Protein; Chemistry; Proinflammatory cytokine; Amyloid (mycology); Tumor necrosis factor alpha; Acute-phase protein; Cytokine; Endocrinology; Immunology; Molecular biology; Internal medicine; Biology; Inflammation; Medicine; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001397849,0.0001947372,0.0002710001,0.0003507904,0.0001180719,0.0002499433,0.00006788907,0.000222336,0.0004854176],"category_scores_gemma":[0.0001088794,0.0001527347,0.0001892785,0.0001620506,0.0001928986,0.0001701076,0.0001347933,0.0004443208,0.0002853715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001638614,"about_ca_system_score_gemma":0.00009199539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002239521,"about_ca_topic_score_gemma":0.0003373393,"domain_scores_codex":[0.9998515,0.00002357165,0.0000194389,0.00003608184,0.00002787072,0.00004154191],"domain_scores_gemma":[0.999813,0.00002707238,0.00005529764,0.00001621745,0.0000243957,0.00006398917],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003335631,0.00001676204,0.001391629,0.00001626123,0.000002907406,0.00006618412,0.00002530962,0.00002567146,0.997708,0.00002191602,0.000006388298,0.0003854162],"study_design_scores_gemma":[0.00004666282,0.00138219,0.1074764,0.00001010501,0.00004965564,0.000731364,0.0001767632,0.0009482645,0.8880758,0.0001159822,0.0009724945,0.00001424026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972618,0.001234708,0.0006515595,0.00002414195,0.00000706905,0.00001377611,0.0003263048,0.00002456609,0.0004561424],"genre_scores_gemma":[0.9977058,0.000462874,0.000696846,0.00003267941,0.00001311815,0.00004030749,0.0003362265,0.000006209359,0.0007060547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004854176,"threshold_uncertainty_score":0.001623869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01673344399621057,"score_gpt":0.2476776345059586,"score_spread":0.230944190509748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}