{"id":"W2063354139","doi":"10.2174/157016410790979644","title":"An Update on Prion Biology and Proteomics","year":2010,"lang":"en","type":"article","venue":"Current Proteomics","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Proteomics; Neurodegeneration; Biology; Mechanism (biology); Prion protein; Gene isoform; Scrapie; Infectivity; Neurotoxicity; Computational biology; Virology; Toxicity; Genetics; Chemistry; Disease; Medicine; Gene; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003378269,0.001522235,0.002531556,0.005087193,0.000776151,0.00393508,0.00215478,0.003726885,0.004304093],"category_scores_gemma":[0.004513386,0.0007376152,0.0007735139,0.003909274,0.001579444,0.007422789,0.00137763,0.006274791,0.004152697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001523361,"about_ca_system_score_gemma":0.002002156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001212065,"about_ca_topic_score_gemma":0.002967151,"domain_scores_codex":[0.9990268,0.0001645998,0.0001932914,0.0001223249,0.0004064715,0.00008657166],"domain_scores_gemma":[0.9958659,0.001916792,0.0002490504,0.0002204832,0.00136587,0.0003819295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003194153,0.0001524795,0.0004449248,0.007074386,0.0002003871,0.0007221265,0.000135807,0.0001886906,0.004850759,0.008464034,0.4772962,0.5001507],"study_design_scores_gemma":[0.00002176817,0.00004950527,0.0002701411,0.0006050708,0.00006453571,0.0007734783,0.00003345371,0.00006691129,0.0005308308,0.002454079,0.99511,0.00002034131],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002325961,0.9731306,0.001243835,0.008533161,0.01483065,0.00000982156,0.00009339629,0.00008490053,0.001840975],"genre_scores_gemma":[0.001699992,0.9571729,0.002433714,0.009844376,0.02328547,0.00003186314,0.0002967334,0.00002630677,0.005208715],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005087193,"threshold_uncertainty_score":0.01786619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009236432333425654,"score_gpt":0.3122058657792087,"score_spread":0.302969433445783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}