{"id":"W2063387096","doi":"10.1021/ol047602y","title":"Aryl Annulation of Cyclic Ketones via a Magnesium Carbometalation−6-π- Electrocyclization Protocol","year":2005,"lang":"en","type":"article","venue":"Organic Letters","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Annulation; Aryl; Ketone; Trifluoromethanesulfonate; Electrophile; Enol; Magnesium; Aromatization; Alcohol; Medicinal chemistry; Oxalyl chloride; Organic chemistry; Propargyl; Propargyl alcohol; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002040713,0.0001986708,0.000218395,0.0001639151,0.00008075915,0.00002812942,0.000159386,0.000116446,0.005055006],"category_scores_gemma":[0.0001560781,0.0002140566,0.00008655181,0.0005544913,0.00005810995,0.0003129785,0.00003820204,0.000123766,0.0000679619],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002412941,"about_ca_system_score_gemma":0.000064874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001905612,"about_ca_topic_score_gemma":0.00001101635,"domain_scores_codex":[0.9984571,0.000031696,0.0005373313,0.0003339046,0.0004117777,0.0002281834],"domain_scores_gemma":[0.9989842,0.00009075172,0.0003423617,0.0003900247,0.0001289918,0.00006365473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004131273,0.00007109407,0.008518163,0.000139112,0.00002545494,6.544921e-7,0.0001355887,0.0007344387,0.9875213,0.0001155908,0.0004873099,0.002209994],"study_design_scores_gemma":[0.001112136,0.00001589322,0.01123849,0.00001747457,0.0000670075,0.0000273003,0.00001519096,0.005552979,0.9754838,0.0001164661,0.006078437,0.0002748047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7692488,0.00002268949,0.2132738,0.004642376,0.0001707505,0.01025619,0.00001628782,0.0003908039,0.001978332],"genre_scores_gemma":[0.9889312,0.000001058682,0.004098038,0.0007289804,0.0006667418,0.004474365,0.0002513501,0.00007693995,0.0007712659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2196825,"threshold_uncertainty_score":0.9958545,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009588678435636266,"score_gpt":0.2596598970510495,"score_spread":0.2500712186154132,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}