{"id":"W2063441603","doi":"10.1006/bbrc.2001.4889","title":"RACK1, a Protein Kinase C Scaffolding Protein, Interacts with the PH Domain of p120GAP","year":2001,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Heterotrimeric G protein; Immunoprecipitation; GTPase-activating protein; Phosphorylation; Biochemistry; Chemistry; Protein subunit; Fusion protein; SH3 domain; Cell biology; GTPase; C2 domain; Scaffold protein; Serine; Small GTPase; G protein; Biology; Recombinant DNA; Signal transduction; Proto-oncogene tyrosine-protein kinase Src; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005584048,0.0001374779,0.0001453067,0.00005840735,0.0003371339,0.00005093955,0.0006412619,0.0001018069,0.00001129236],"category_scores_gemma":[0.0002375497,0.00008799989,0.0000686199,0.0004234159,0.001173454,0.000009705631,0.0005682049,0.0003017087,0.000005651838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001745824,"about_ca_system_score_gemma":0.00009503328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003904039,"about_ca_topic_score_gemma":0.00001244969,"domain_scores_codex":[0.9985573,0.0003032627,0.0001988863,0.0002872259,0.0003508337,0.0003025114],"domain_scores_gemma":[0.9983422,0.00008272043,0.00007814716,0.001017007,0.0003337373,0.0001462555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000234256,0.0002331972,0.00002124628,0.00003036921,0.00002641598,0.000001619273,0.00004481891,5.002818e-7,0.9926482,0.004377587,0.0002628543,0.002118877],"study_design_scores_gemma":[0.0004246758,0.0002902168,0.0001457564,0.000160932,0.000007217789,0.000008250365,0.0001775273,0.0001284722,0.9789512,0.0009239877,0.01864592,0.000135799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912483,0.001146744,0.0004304207,0.005677215,0.000003098829,0.0007476482,0.00001125089,0.00001217989,0.000723164],"genre_scores_gemma":[0.9968855,0.0001346186,0.002187902,0.00005804692,0.00009252768,0.0002681544,0.00006321393,0.00001561869,0.0002943646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01838307,"threshold_uncertainty_score":0.432364,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04201898058258823,"score_gpt":0.3345140070702154,"score_spread":0.2924950264876272,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}