{"id":"W2063441603","doi":"10.1006/bbrc.2001.4889","title":"RACK1, a Protein Kinase C Scaffolding Protein, Interacts with the PH Domain of p120GAP","year":2001,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Heterotrimeric G protein; Immunoprecipitation; GTPase-activating protein; Phosphorylation; Biochemistry; Chemistry; Protein subunit; Fusion protein; SH3 domain; Cell biology; GTPase; C2 domain; Scaffold protein; Serine; Small GTPase; G protein; Biology; Recombinant DNA; Signal transduction; Proto-oncogene tyrosine-protein kinase Src; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001765977,0.0005877175,0.0002555083,0.000460921,0.0009424441,0.000738323,0.0005140158,0.0006367326,0.001760404],"category_scores_gemma":[0.0003788863,0.0003276558,0.0003815441,0.000268328,0.0003184732,0.0006059755,0.0007002912,0.0007342201,0.001812338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001130469,"about_ca_system_score_gemma":0.0002153375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001092389,"about_ca_topic_score_gemma":0.001509241,"domain_scores_codex":[0.999791,0.00002432914,0.00000629099,0.00004867343,0.00005989298,0.00006972266],"domain_scores_gemma":[0.9998103,0.00003352901,0.00005221276,0.00001841037,0.00002324285,0.00006235309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00029655,0.00003467111,0.001074676,0.00008150678,0.00001727597,0.0003939011,0.00005082714,0.0001855975,0.9929811,0.0009449187,0.0007337367,0.003205194],"study_design_scores_gemma":[0.00005993754,0.0001102832,0.03840401,0.00002305342,0.0000424079,0.004027097,0.0001521573,0.007080844,0.9325956,0.00074623,0.01672722,0.00003124071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874888,0.003227647,0.003084585,0.0006094545,0.00006444699,0.00001583734,0.0002721675,0.00015089,0.005086179],"genre_scores_gemma":[0.9918282,0.001030872,0.001702951,0.0001473582,0.00003503708,0.00001951547,0.001135924,0.00004693292,0.004053305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001760404,"threshold_uncertainty_score":0.008202136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04201898058258823,"score_gpt":0.3345140070702154,"score_spread":0.2924950264876272,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}