{"id":"W2063565113","doi":"10.1002/stem.301","title":"Development and Function of Myeloid-Derived Suppressor Cells Generated From Mouse Embryonic and Hematopoietic Stem Cells","year":2010,"lang":"en","type":"article","venue":"Stem Cells","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":151,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; Susan G. Komen","keywords":"Biology; Myeloid-derived Suppressor Cell; Immunology; Stem cell; Adoptive cell transfer; Cancer research; FOXP3; Population; Immune system; IL-2 receptor; Haematopoiesis; Embryonic stem cell; T cell; Cell biology; Suppressor; Cancer; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002181645,0.0003619387,0.00013699,0.0004031976,0.00008354255,0.0002413303,0.0001707516,0.0002387253,0.0005140466],"category_scores_gemma":[0.00010549,0.000119602,0.0001742738,0.0001320271,0.000168933,0.0001351442,0.0001648561,0.0004387125,0.0003849613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001611261,"about_ca_system_score_gemma":0.0001613409,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001620358,"about_ca_topic_score_gemma":0.0001799254,"domain_scores_codex":[0.9998637,0.00002042492,0.00002175418,0.00002847948,0.00004537565,0.00002016395],"domain_scores_gemma":[0.999926,0.000008136238,0.0000247668,0.00001304091,0.000009889037,0.00001821212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008466531,0.0000194714,0.0004422047,0.00003045205,0.000003430534,0.00005410947,0.00002201336,0.00008596358,0.9948158,0.0006380152,0.00003060744,0.003773247],"study_design_scores_gemma":[0.00001972461,0.0003074454,0.005283911,0.00001194786,0.00002075285,0.0003988148,0.00001638226,0.0007699081,0.9863127,0.0001713257,0.006682734,0.000004258271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9685402,0.01002229,0.01609875,0.000111827,0.00004298912,0.0001403276,0.001129853,0.0002167833,0.003697058],"genre_scores_gemma":[0.9841295,0.00300159,0.007312243,0.00005845193,0.00001770888,0.00008934983,0.001712333,0.00004145136,0.00363743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005140466,"threshold_uncertainty_score":0.001719713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0106807188435239,"score_gpt":0.1982652357799805,"score_spread":0.1875845169364566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}