{"id":"W2063582896","doi":"10.1182/blood-2009-04-214593","title":"Wild-type FOXP3 is selectively active in CD4+CD25hi regulatory T cells of healthy female carriers of different FOXP3 mutations","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"FOXP3; Biology; X-inactivation; Regulatory T cell; Mutation; Immunology; Immune system; Cell biology; Genetics; X chromosome; Molecular biology; T cell; Gene; IL-2 receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008759148,0.0001490888,0.0003324444,0.0002246729,0.00007353588,0.000003020352,0.0001009994,0.0002000194,0.0004823206],"category_scores_gemma":[0.00004181443,0.000143994,0.0001062273,0.0002495672,0.00009977971,0.00009685576,0.0000171014,0.0002746089,0.00003577156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005256154,"about_ca_system_score_gemma":0.00009788654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001282079,"about_ca_topic_score_gemma":0.00003163369,"domain_scores_codex":[0.9989304,0.0001652949,0.000403208,0.0002287253,0.00004523273,0.0002271218],"domain_scores_gemma":[0.999273,0.00008116166,0.0002600915,0.0002074026,0.0001576614,0.00002068904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007432866,0.001117904,0.00333873,0.00002452768,0.0002157837,8.818777e-7,0.002998533,0.00001178685,0.9887565,0.0001516295,0.001373622,0.001266819],"study_design_scores_gemma":[0.002184683,0.00124158,0.09642106,0.00004135626,0.00008342259,0.000009873225,0.001237266,0.000003695614,0.8976089,0.00008783344,0.0009634151,0.0001168724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965454,0.0006131333,0.00002147277,0.0001192575,0.000813533,0.0002536168,0.00001393093,0.00002325926,0.001596362],"genre_scores_gemma":[0.9979005,0.00007820317,0.0000277591,0.0002177092,0.00001400505,0.000007188471,0.00005396249,0.00001046039,0.00169023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09308233,"threshold_uncertainty_score":0.5871903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00993274843979748,"score_gpt":0.2391115823460308,"score_spread":0.2291788339062333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}