{"id":"W2063601990","doi":"10.1081/bio-120018000","title":"The Intravascular Persistence and Methemoglobin Formation of Hemolink™ (Hemoglobin Raffimer) in Dogs","year":2003,"lang":"en","type":"article","venue":"Artificial Cells Blood Substitutes and Biotechnology","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Association of Radiation Oncology; Research Canada; Apotex (Canada); MASSolutions (Canada)","funders":"","keywords":"Methemoglobin; Hemoglobin; Chemistry; Tetramer; Volume of distribution; Half-life; Chromatography; Blood substitute; Animal science; Internal medicine; Biochemistry; Medicine; Pharmacokinetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003480196,0.0001480837,0.0001779563,0.00007141791,0.0001462022,0.0000229266,0.0001146826,0.0003476482,0.00000273058],"category_scores_gemma":[0.0001127541,0.0001133493,0.00004899628,0.0001966858,0.0004203979,0.00001046533,0.00006130242,0.000138253,0.000001475734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006356969,"about_ca_system_score_gemma":0.00003122916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003679903,"about_ca_topic_score_gemma":0.0002285884,"domain_scores_codex":[0.9990084,0.00007040706,0.0002971412,0.0002938737,0.0000809095,0.0002492502],"domain_scores_gemma":[0.9995379,0.00002830902,0.00009291575,0.0002572637,0.00004273075,0.00004083381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000428575,0.00003974682,0.0003793331,0.00002101677,0.00002924067,0.0000033019,0.00006032735,0.00001626677,0.9730005,0.01181463,0.00003204111,0.01456079],"study_design_scores_gemma":[0.0003589177,0.0001955377,0.0001347074,0.000008976712,0.00004045636,0.0000822589,0.0004195758,0.0001054648,0.9878142,0.001757354,0.008946594,0.0001359394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946477,0.003620438,0.0008082052,0.0003557308,0.0001400499,0.0002049128,0.000004768083,0.0000133808,0.0002047787],"genre_scores_gemma":[0.9964287,0.002481954,0.0009561541,0.00006393509,0.0000236779,0.000008413497,0.000009790243,0.000007928138,0.00001948134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01481376,"threshold_uncertainty_score":0.4622249,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008802930167920822,"score_gpt":0.2007119146332325,"score_spread":0.1919089844653117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}