{"id":"W2063624336","doi":"10.1093/nar/gkp672","title":"H-NS binds with high affinity to the Tn10 transpososome and promotes transpososome stabilization","year":2009,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Tn10; Biology; Transposase; Transposable element; DNA; Binding site; Biophysics; DNA-binding protein; Plasma protein binding; Transposition (logic); Molecular biology; Cell biology; Gene; Biochemistry; Mutant; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002290705,0.0003500951,0.0003491312,0.0001425906,0.0002659976,0.0003661455,0.0002389414,0.0004105287,0.001762976],"category_scores_gemma":[0.0003568835,0.0002327394,0.0002547962,0.0000849723,0.0003353223,0.0002394532,0.0003657085,0.000384787,0.0007032081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005296034,"about_ca_system_score_gemma":0.0002583951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003585236,"about_ca_topic_score_gemma":0.004470958,"domain_scores_codex":[0.9996351,0.00006487365,0.0000190812,0.00006821437,0.0001393455,0.000073394],"domain_scores_gemma":[0.9997112,0.00008438779,0.00003970528,0.00002538948,0.00004665958,0.00009254549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005436662,0.00001747098,0.0005644754,0.00002876857,0.000008311566,0.00002950423,0.0000140981,0.000105833,0.9986011,0.00005676897,0.00002767258,0.0004914529],"study_design_scores_gemma":[0.00000611953,0.0001506223,0.01049233,0.000004329467,0.000006575342,0.000109421,0.00006863461,0.001525081,0.9860302,0.00006254476,0.001535106,0.000009046883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917707,0.0009475719,0.005353886,0.00008908438,0.00001670312,0.00002127745,0.00007381657,0.00006076354,0.00166615],"genre_scores_gemma":[0.9957201,0.000210499,0.002144515,0.00005358643,0.000005505743,0.000007617165,0.0001451657,0.00001346402,0.001699696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003585236,"threshold_uncertainty_score":0.007128775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0201611136786103,"score_gpt":0.2809973223144441,"score_spread":0.2608362086358338,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}