{"id":"W2063653868","doi":"10.1371/journal.pone.0097675","title":"Bacterial Peptidoglycan Stimulates Adipocyte Lipolysis via NOD1","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Lipolysis; NOD1; Hormone-sensitive lipase; Adipocyte; Insulin resistance; Protein kinase A; Endocrinology; Biology; Adipose tissue; Internal medicine; Inflammation; Kinase; MAPK/ERK pathway; Chemistry; Biochemistry; Insulin; NOD2; Receptor; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001231976,0.0003876788,0.0001638161,0.0001704304,0.0001186235,0.000183307,0.0001029387,0.0001670166,0.001863567],"category_scores_gemma":[0.00007063677,0.0001022438,0.0002851401,0.00009691512,0.0001749995,0.000157778,0.000278926,0.00056703,0.0003877856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001829461,"about_ca_system_score_gemma":0.0001401164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002353238,"about_ca_topic_score_gemma":0.0004493557,"domain_scores_codex":[0.9999007,0.00002049299,0.000008379836,0.00002328967,0.0000210105,0.00002617871],"domain_scores_gemma":[0.9999458,0.000006630003,0.00001618141,0.000004619479,0.000005730953,0.00002107292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004310937,0.00005075493,0.000200884,0.00007868834,0.000004424372,0.00006452375,0.00001006239,0.00003587098,0.9980074,0.00006117421,0.00004860337,0.001006599],"study_design_scores_gemma":[0.000138789,0.001402514,0.0199021,0.00004268108,0.00003144292,0.0006341859,0.0001343266,0.001421575,0.9717131,0.0002642045,0.004300804,0.00001430866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902002,0.002933204,0.002490344,0.0003183463,0.00009670609,0.00004501095,0.0005808173,0.00009256723,0.003242805],"genre_scores_gemma":[0.9906446,0.001676114,0.002473504,0.0002007374,0.00002694059,0.00007625946,0.0007158238,0.00001700581,0.004168989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001863567,"threshold_uncertainty_score":0.006234288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0160760855137173,"score_gpt":0.2168496358411095,"score_spread":0.2007735503273922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}