{"id":"W2063662864","doi":"10.1038/ng.2532","title":"The genomic landscape of hypodiploid acute lymphoblastic leukemia","year":2013,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":728,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"National Institute of General Medical Sciences; National Cancer Institute","keywords":"Biology; Aneuploidy; Cancer research; Bruton's tyrosine kinase; Exome sequencing; Receptor tyrosine kinase; Genetics; Signal transduction; Leukemia; Exome; Tyrosine kinase; Gene; Chromosome; Mutation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001827513,0.0001455285,0.0002389772,0.0008139546,0.0002736317,0.0008424469,0.0003155241,0.0003636846,0.003598452],"category_scores_gemma":[0.0009567423,0.0001536519,0.0000900601,0.0007630043,0.0004726895,0.0005066106,0.0005661694,0.0004773037,0.0003482457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003701092,"about_ca_system_score_gemma":0.0001980014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005414635,"about_ca_topic_score_gemma":0.0007842208,"domain_scores_codex":[0.9997787,0.00005312671,0.000009469012,0.00005684534,0.00005380751,0.00004820037],"domain_scores_gemma":[0.9996991,0.0001153483,0.00008967501,0.00001980813,0.00002675038,0.00004942925],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001918618,0.0001096149,0.2692672,0.0004077756,0.0002450936,0.005429137,0.001419125,0.006345946,0.4621689,0.02851446,0.006749085,0.217425],"study_design_scores_gemma":[0.0001195415,0.0005132178,0.8077367,0.0001344874,0.0003808546,0.01642592,0.002772924,0.004626135,0.03030368,0.08116115,0.05576433,0.00006101676],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9781898,0.006941479,0.001690686,0.004181339,0.0000348729,0.00001019911,0.0008499566,0.00006915583,0.008032557],"genre_scores_gemma":[0.9958557,0.002159177,0.0003250576,0.0005028813,0.00006356685,0.000005553773,0.0002874106,0.00002171495,0.0007789484],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003598452,"threshold_uncertainty_score":0.01203799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006995370297557125,"score_gpt":0.2575525198971469,"score_spread":0.2505571495995897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}