{"id":"W2063738326","doi":"10.1016/j.vaccine.2012.03.075","title":"Novel CD8+ T cell-based vaccine stimulates Gp120-specific CTL responses leading to therapeutic and long-term immunity in transgenic HLA-A2 mice","year":2012,"lang":"en","type":"article","venue":"Vaccine","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"CTL*; Biology; Cytotoxic T cell; CD8; Virology; T cell; Immunology; Immune system; Molecular biology; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00109506,0.0004895137,0.0006998031,0.0006163063,0.0003278437,0.0000425889,0.0004220163,0.0003579168,0.0008803919],"category_scores_gemma":[0.00007867506,0.0004347149,0.0001498201,0.0005475504,0.0000384406,0.00027825,0.00008608654,0.000610725,0.0003433231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001014929,"about_ca_system_score_gemma":0.00007601221,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001063055,"about_ca_topic_score_gemma":0.00006029493,"domain_scores_codex":[0.9971749,0.0006562515,0.0006982195,0.0004346824,0.00006572662,0.0009702149],"domain_scores_gemma":[0.9979948,0.001033877,0.0001569634,0.000666567,0.00007696449,0.00007084104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01008244,0.0006849238,0.06315234,0.0000524652,0.0001468259,0.000004138084,0.001516571,0.00003853632,0.9169532,0.00002426997,0.0001378404,0.007206459],"study_design_scores_gemma":[0.00690972,0.0004992379,0.4728077,0.0001264551,0.00005821911,0.00008512695,0.0001389776,0.000005632745,0.5119761,0.000004841835,0.006921817,0.000466168],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9306892,0.0655027,0.001451671,0.0008164883,0.0006155557,0.0007495589,0.00003004029,0.0001034277,0.00004142815],"genre_scores_gemma":[0.9958594,0.00102101,0.0001575843,0.0006483847,0.0000625387,0.000047286,0.00007386889,0.00007414124,0.002055801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4096554,"threshold_uncertainty_score":0.9998105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02821956400189336,"score_gpt":0.2773637447960766,"score_spread":0.2491441807941833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}