{"id":"W2063756018","doi":"10.1158/0008-5472.sabcs11-p3-16-01","title":"P3-16-01: Safety Profile and Clinical Activity of Single-Agent BKM120, a Pan-Class I PI3K Inhibitor, for the Treatment of Patients with Metastatic Breast Carcinoma.","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Internal medicine; Breast cancer; Adverse effect; Gastroenterology; Metastatic breast cancer; Cancer; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004050531,0.0003138147,0.0005292282,0.000139161,0.0001740278,0.0004195125,0.000309677,0.0004349797,0.002323976],"category_scores_gemma":[0.0003988394,0.0001215133,0.0002963643,0.0002462812,0.0002715696,0.0003281789,0.0001493716,0.001112275,0.0005450207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004273709,"about_ca_system_score_gemma":0.0006050789,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003557584,"about_ca_topic_score_gemma":0.0006988981,"domain_scores_codex":[0.9999005,0.00003145761,0.000008465669,0.00001849467,0.00002202862,0.00001911647],"domain_scores_gemma":[0.9998052,0.00003056261,0.00006030052,0.00001579875,0.00001164063,0.00007655075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2172151,0.01719995,0.04782587,0.001204504,0.0007017706,0.001548708,0.0003083211,0.002679451,0.1959714,0.0003300114,0.007459584,0.5075554],"study_design_scores_gemma":[0.09504908,0.5940329,0.1840843,0.0001465855,0.0009111057,0.007864933,0.0001512157,0.006119059,0.08796933,0.0004789539,0.02314065,0.0000519145],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951068,0.0025195,0.0003423027,0.0001814656,0.0000236995,0.000163567,0.000480333,0.00005262189,0.001129651],"genre_scores_gemma":[0.9967361,0.000804309,0.0003417979,0.0001274403,0.00003440996,0.0001247783,0.0008250517,0.000009414123,0.0009966275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002323976,"threshold_uncertainty_score":0.007774532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1623529300358657,"score_gpt":0.4113457694450203,"score_spread":0.2489928394091546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}