{"id":"W2063791455","doi":"10.1056/nejmsb033476","title":"Data Safety and Monitoring Boards","year":2004,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Ethics in Clinical Research","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Medicine; Data monitoring committee; Clinical trial; Institutional review board; Safety monitoring; On board; Public relations; Medical emergency; Surgery; Pathology; Bioinformatics; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.00727981,0.00009895805,0.0004589353,0.0001341567,0.00005214885,0.000009616117,0.0003162716,0.0001360277,0.00008851124],"category_scores_gemma":[0.02021687,0.00006049127,0.00003027429,0.0001434211,0.0002580356,0.0001196305,0.0001561917,0.00191485,0.000003777772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006949466,"about_ca_system_score_gemma":0.0007315707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001129136,"about_ca_topic_score_gemma":0.00004369127,"domain_scores_codex":[0.9976633,0.00005323456,0.0006773551,0.0001729106,0.001239232,0.000193993],"domain_scores_gemma":[0.9957471,0.002541347,0.0001923538,0.0004841363,0.000394141,0.0006409509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.009255105,0.0003148401,0.1022372,0.000629617,0.0006317903,0.004225088,0.003117058,0.00007451283,0.009945777,0.008105588,0.006212551,0.8552509],"study_design_scores_gemma":[0.3225468,0.01161101,0.17094,0.0128906,0.0008777172,0.01137015,0.001354564,0.00005699138,0.001636847,0.09036544,0.3760096,0.0003403092],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6089535,0.01733183,0.007903084,0.3507508,0.002994763,0.0003166861,0.00001446242,0.00003524729,0.01169962],"genre_scores_gemma":[0.9572594,0.0193373,0.007423666,0.0006676379,0.01421537,1.450505e-7,0.00000584925,0.00001997781,0.001070682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8549106,"threshold_uncertainty_score":0.9880363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4684138923889489,"score_gpt":0.5664905981517444,"score_spread":0.09807670576279548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}