{"id":"W2063869251","doi":"10.1371/journal.pone.0045382","title":"Melanoma-Associated Cancer-Testis Antigen 16 (CT16) Regulates the Expression of Apoptotic and Antiapoptotic Genes and Promotes Cell Survival","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Turun Yliopistollinen Keskussairaala; Syöpäjärjestöt","keywords":"Gene silencing; Melanoma; Biology; Cancer research; DNA methylation; Apoptosis; DKK1; Cancer cell; Cancer; Gene expression; Molecular biology; Gene; Wnt signaling pathway; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008892467,0.0002335978,0.0001856271,0.0003324898,0.0001374111,0.000214882,0.00007193568,0.0001382391,0.001268376],"category_scores_gemma":[0.00009056537,0.000104814,0.0002200973,0.0002265417,0.0001448377,0.0001584646,0.0001372762,0.0002430981,0.0003488077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001993845,"about_ca_system_score_gemma":0.0001632012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003360973,"about_ca_topic_score_gemma":0.0006269102,"domain_scores_codex":[0.9999125,0.0000110063,0.000009115038,0.00002563187,0.00002215401,0.00001963849],"domain_scores_gemma":[0.9999033,0.000008954235,0.00004028493,0.000008982305,0.00001483043,0.00002371282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000773892,0.00001032947,0.001385306,0.0000426989,0.000004607551,0.00003916538,0.00001312338,0.00004211002,0.9969939,0.00003400599,0.00002567735,0.001331696],"study_design_scores_gemma":[0.00001538292,0.0004099557,0.05276791,0.00001587928,0.00002510527,0.0006037207,0.00005898415,0.0004368588,0.9403806,0.00006355625,0.00521641,0.000005632309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942449,0.002967927,0.00113326,0.00003007762,0.0000158891,0.00002047379,0.0005311449,0.00004283499,0.001013515],"genre_scores_gemma":[0.9920545,0.001914445,0.001592551,0.00002535222,0.000006488004,0.00002703144,0.001025253,0.00001297699,0.003341378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001268376,"threshold_uncertainty_score":0.004243195,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02776344269007179,"score_gpt":0.2258514782422765,"score_spread":0.1980880355522047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}