{"id":"W2063949146","doi":"10.1097/00126334-200309011-00013","title":"Mitochondrial Toxicity in the Era of HAART: Evaluating Venous Lactate and Peripheral Blood Mitochondrial DNA in HIV-Infected Patients Taking Antiretroviral Therapy","year":2003,"lang":"en","type":"review","venue":"JAIDS Journal of Acquired Immune Deficiency Syndromes","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; Providence Health Care; HIV Legal Network; University of British Columbia","funders":"","keywords":"Mitochondrial toxicity; Stavudine; Lamivudine; Hyperlactatemia; Didanosine; Mitochondrial DNA; Biology; Asymptomatic; Internal medicine; Nucleoside analogue; Viral load; Zidovudine; Gastroenterology; Medicine; Pharmacology; Toxicity; Immunology; Virology; Nucleoside; Viral disease; Human immunodeficiency virus (HIV); Genetics; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005808726,0.0002613206,0.0005869805,0.0005703954,0.0004992225,0.0008416317,0.0002829681,0.0004564403,0.000439493],"category_scores_gemma":[0.002619028,0.0002532274,0.0001360921,0.0009274181,0.0002323406,0.0003562136,0.0003158603,0.0005787309,0.0001021191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004055522,"about_ca_system_score_gemma":0.0003969758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004902455,"about_ca_topic_score_gemma":0.007533941,"domain_scores_codex":[0.9996227,0.0001186919,0.0000395512,0.00004326849,0.0001194524,0.00005640261],"domain_scores_gemma":[0.9991052,0.0002046015,0.0002739787,0.00002512395,0.0001410451,0.0002500974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000494379,0.00008494397,0.9932095,0.00002714385,0.00003452808,0.0002579921,0.000159788,0.00005838921,0.001545026,0.000009827654,0.00003838332,0.004080125],"study_design_scores_gemma":[0.00001533033,0.0008117619,0.9973751,0.00001255006,0.00003402552,0.0005448516,0.000217832,0.000386971,0.0004241051,0.00001346953,0.0001605215,0.000003554553],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9986416,0.0008292394,0.00008482806,0.00004108849,0.000004417736,0.0000208968,0.00006556881,0.000003343376,0.0003092055],"genre_scores_gemma":[0.9992448,0.0002858814,0.0001675745,0.00005623952,0.00001031258,0.00001397182,0.00009786371,0.000001033591,0.0001222859],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.004902455,"threshold_uncertainty_score":0.009747863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04031814044689733,"score_gpt":0.344507449152774,"score_spread":0.3041893087058767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}