{"id":"W2064020008","doi":"10.1016/s0168-3659(00)00237-6","title":"NMR imaging investigations of drug delivery devices using a flow-through USP dissolution apparatus","year":2000,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":55,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Dissolution; Dissolution testing; Drug delivery; Drug; Chemistry; Diffusion; Dosage form; Delivery system; Biomedical engineering; Chromatography; Pharmacology; Medicine; Organic chemistry; Biopharmaceutics Classification System; Thermodynamics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005753483,0.0003151808,0.0003212205,0.0003341081,0.0003711858,0.0004020195,0.0003717889,0.0005612784,0.0008062131],"category_scores_gemma":[0.0007449577,0.0002859906,0.0002048564,0.0001999025,0.0004073614,0.0007357758,0.0002295371,0.0004279389,0.0002706974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002460744,"about_ca_system_score_gemma":0.0002761516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008259183,"about_ca_topic_score_gemma":0.000615388,"domain_scores_codex":[0.9997874,0.00005992934,0.00002159873,0.00004219669,0.00005787605,0.00003103802],"domain_scores_gemma":[0.999454,0.0002905509,0.00008023097,0.00004686293,0.000105019,0.0000234765],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008970167,0.00001915055,0.000090282,0.00002357879,0.000002509936,0.00002625976,0.00002765952,0.00002382081,0.9982754,0.00005065071,0.00001487019,0.001356156],"study_design_scores_gemma":[0.00002222912,0.0003442813,0.002147871,0.000004968844,0.00001986344,0.0001917751,0.00003428588,0.0008315006,0.9955601,0.00001898585,0.000816484,0.000007743403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9736218,0.001990306,0.02227542,0.0001567241,0.00002796665,0.0001058222,0.0001865232,0.0001150817,0.001520282],"genre_scores_gemma":[0.9501547,0.002170639,0.04366846,0.0001093691,0.00003962458,0.0001031757,0.0003059739,0.00007056183,0.00337756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008259183,"threshold_uncertainty_score":0.003042758,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06069953379188094,"score_gpt":0.3743580085240186,"score_spread":0.3136584747321377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}