{"id":"W2064037605","doi":"10.1038/nprot.2009.201","title":"EOS lentiviral vector selection system for human induced pluripotent stem cells","year":2009,"lang":"en","type":"article","venue":"Nature Protocols","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; SickKids Foundation","funders":"Canadian Institutes of Health Research","keywords":"Induced pluripotent stem cell; Reprogramming; Viral vector; Biology; Embryonic stem cell; Stem cell; Cell biology; Computational biology; Cell; Genetics; Gene; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003541037,0.000266465,0.0002498289,0.00009827787,0.0002331743,0.00009331759,0.0003808471,0.0007357519,0.000005094432],"category_scores_gemma":[0.00001755756,0.0002446391,0.0001950256,0.0001738858,0.00002235862,0.000009777919,0.00006877945,0.0004770095,0.00001839369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001270977,"about_ca_system_score_gemma":0.0001122394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006038929,"about_ca_topic_score_gemma":0.00001178876,"domain_scores_codex":[0.998024,0.0001314026,0.0003136075,0.0006310208,0.00037724,0.0005226659],"domain_scores_gemma":[0.999034,0.00001127256,0.0001491685,0.0003953579,0.0002827811,0.0001274061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003253858,0.0001363492,0.000119732,0.0002292811,0.00004131236,0.000003326961,0.00001019812,0.00001290139,0.9937223,0.0004631881,0.002092158,0.002843837],"study_design_scores_gemma":[0.00149163,0.001728464,0.0004200258,0.0001088272,0.00001284347,0.0000126732,0.00002303135,0.00009605703,0.963659,0.0000452997,0.03213279,0.0002693395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7257419,0.0002529716,0.003600332,0.0004643838,0.0004806286,0.2657982,0.0001124042,0.0002748131,0.003274336],"genre_scores_gemma":[0.9524677,0.000001045662,0.0003503593,0.0001143439,0.0005990954,0.04463918,0.00005933264,0.00003789935,0.001730974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2267258,"threshold_uncertainty_score":0.9976091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02156878170489827,"score_gpt":0.3288731821088641,"score_spread":0.3073044004039658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}