{"id":"W2064037605","doi":"10.1038/nprot.2009.201","title":"EOS lentiviral vector selection system for human induced pluripotent stem cells","year":2009,"lang":"en","type":"article","venue":"Nature Protocols","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; SickKids Foundation","funders":"Canadian Institutes of Health Research","keywords":"Induced pluripotent stem cell; Reprogramming; Viral vector; Biology; Embryonic stem cell; Stem cell; Cell biology; Computational biology; Cell; Genetics; Gene; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006406637,0.0006379523,0.000473566,0.001023361,0.0007030908,0.0006626349,0.0007549493,0.0004509606,0.008235015],"category_scores_gemma":[0.0002774656,0.0005329255,0.0004940006,0.0004827425,0.000292984,0.0004913765,0.0004957427,0.00138749,0.004117976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004200265,"about_ca_system_score_gemma":0.0005900686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000581999,"about_ca_topic_score_gemma":0.001824335,"domain_scores_codex":[0.9993991,0.00007581607,0.000104094,0.0001231612,0.0002026406,0.00009517252],"domain_scores_gemma":[0.999821,0.00003346496,0.00002445766,0.00004620006,0.00003977043,0.00003513975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001947249,0.00009836852,0.0003496107,0.0001099171,0.00001479513,0.0001176552,0.00008937775,0.00009144591,0.977284,0.003000222,0.00231656,0.01633335],"study_design_scores_gemma":[0.00007715251,0.0001461302,0.001832293,0.0000226364,0.00004784003,0.0005639718,0.00001966744,0.001691116,0.9154403,0.000372215,0.07976687,0.00001988609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.4755577,0.004936469,0.4240042,0.001126793,0.001519346,0.004159061,0.02111439,0.007822679,0.05975936],"genre_scores_gemma":[0.4985051,0.005591202,0.2851159,0.00107912,0.0003512564,0.003865341,0.05714905,0.002203726,0.1461392],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.008235015,"threshold_uncertainty_score":0.02754885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02156878170489827,"score_gpt":0.3288731821088641,"score_spread":0.3073044004039658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}