{"id":"W2064047723","doi":"10.1152/ajpcell.00323.2009","title":"Filamin A is required for vimentin-mediated cell adhesion and spreading","year":2009,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Canadian Institutes of Health Research","funders":"Canadian Institutes of Health Research","keywords":"Filamin; Vimentin; Cell biology; Cell adhesion; Phosphorylation; Intermediate filament; Small interfering RNA; Protein kinase A; Chemistry; Focal adhesion; Intermediate Filament Protein; Molecular biology; Cytoskeleton; Biology; Cell; Transfection; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009128406,0.0003285984,0.0001709812,0.0002142366,0.0003562036,0.0004404364,0.0002978329,0.0003895129,0.001370855],"category_scores_gemma":[0.0001920723,0.0001999589,0.0003402311,0.0001222112,0.0001758676,0.0002282652,0.0002704358,0.0004471628,0.0009808545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005140628,"about_ca_system_score_gemma":0.0002345344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002401088,"about_ca_topic_score_gemma":0.002892981,"domain_scores_codex":[0.9998222,0.00002105603,0.0000213444,0.00003330403,0.00006077636,0.00004128957],"domain_scores_gemma":[0.9997863,0.00002973926,0.00007676453,0.00002071958,0.0000322317,0.00005434571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004805426,0.000009575811,0.0001763975,0.00001459978,0.000004191293,0.00005823911,0.000004646308,0.00002135765,0.9990568,0.00003658161,0.00002035444,0.0005493266],"study_design_scores_gemma":[0.00001562876,0.0001014613,0.02297465,0.0000112998,0.0000296175,0.000642252,0.00005641546,0.001490937,0.9713273,0.00007553536,0.003265855,0.000009007717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990909,0.002446409,0.004090266,0.0001138489,0.00003227794,0.00002546044,0.0004936443,0.00009587087,0.00179328],"genre_scores_gemma":[0.9944028,0.0007819412,0.001828091,0.00005314903,0.000007046124,0.00001742067,0.0008853982,0.00002560282,0.001998545],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002401088,"threshold_uncertainty_score":0.004774272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008668324985729043,"score_gpt":0.2626315922931612,"score_spread":0.2539632673074322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}