{"id":"W2064051217","doi":"10.1016/j.bcp.2003.09.004","title":"Methioninase and selenomethionine but not Se-methylselenocysteine generate methylselenol and superoxide in an in vitro chemiluminescent assay: implications for the nutritional carcinostatic activity of selenoamino acids","year":2003,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Selenium in Biological Systems","field":"Nursing","cited_by":170,"is_retracted":false,"has_abstract":false,"ca_institutions":"Fisheries and Oceans Canada","funders":"","keywords":"Chemistry; Superoxide; Biochemistry; Selenium; Glutathione; Superoxide dismutase; Ascorbic acid; Methionine; Enzyme; In vivo; Antioxidant; Amino acid; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001024892,0.0008108303,0.0003528496,0.0004140502,0.0003245531,0.0004702503,0.0006383099,0.0007872434,0.002251699],"category_scores_gemma":[0.0006561027,0.00042738,0.0004021791,0.0002651269,0.0003638038,0.0004508276,0.0004532121,0.0008393063,0.0005037832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003225782,"about_ca_system_score_gemma":0.0003457335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005876768,"about_ca_topic_score_gemma":0.001240697,"domain_scores_codex":[0.9996332,0.0001322862,0.00003822883,0.00004692819,0.00007736759,0.00007193401],"domain_scores_gemma":[0.999268,0.000261648,0.0001060168,0.0001307319,0.0001044182,0.0001290879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007589707,0.0001235192,0.000621524,0.00004180005,0.00001428341,0.00008309526,0.0001028291,0.00001831435,0.996858,0.0002753518,0.00005150746,0.001050758],"study_design_scores_gemma":[0.00003429029,0.0004423966,0.00194201,0.000005535761,0.00001450687,0.000219476,0.00005643569,0.000200925,0.9964748,0.00009438535,0.0005117317,0.000003500599],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871325,0.001335233,0.009493807,0.0002795252,0.0001143267,0.00006080038,0.0001519229,0.00007924361,0.001352556],"genre_scores_gemma":[0.9820206,0.0008910425,0.008865493,0.0001232063,0.00004730547,0.00008820673,0.000796219,0.00003521991,0.007132798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002251699,"threshold_uncertainty_score":0.007532656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05050420139984541,"score_gpt":0.3387683513511411,"score_spread":0.2882641499512957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}