{"id":"W2064102695","doi":"10.1074/jbc.m500304200","title":"Proliferating Cell Nuclear Antigen (PCNA) May Function as a Double Homotrimer Complex in the Mammalian Cell","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Northeast Cancer Centre","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Proliferating cell nuclear antigen; Chromatin; Trimer; Nuclear protein; DNA replication; Cell biology; Chemistry; Molecular biology; Biology; DNA; Biophysics; Biochemistry; Dimer; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001457411,0.0003130933,0.0002994998,0.0002150505,0.0002833091,0.0004722999,0.0002367359,0.0003248713,0.000740896],"category_scores_gemma":[0.0001666191,0.000175819,0.0003028002,0.0001670058,0.0002573294,0.0002854981,0.0002832669,0.0003742838,0.0005139607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002838525,"about_ca_system_score_gemma":0.0001846169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003174991,"about_ca_topic_score_gemma":0.0004089347,"domain_scores_codex":[0.9997887,0.00002067916,0.00001786521,0.0001015846,0.00004067696,0.00003051393],"domain_scores_gemma":[0.9998904,0.00001700529,0.00001922337,0.00002657678,0.00001093709,0.000035831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004006713,0.00001939344,0.0003739576,0.0000304579,0.000008616709,0.00007225217,0.00002758378,0.00007652224,0.9964234,0.0002680411,0.00005747079,0.00260219],"study_design_scores_gemma":[0.00002106629,0.0004041671,0.007230217,0.000007377585,0.0000328584,0.0006805066,0.00006246332,0.002552842,0.9789279,0.0004857696,0.009581154,0.00001360327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9752678,0.003945659,0.01762064,0.0001757933,0.0001528956,0.00006738533,0.0001065492,0.0002148647,0.002448397],"genre_scores_gemma":[0.9837954,0.0009341086,0.01035736,0.00009547527,0.00003802335,0.00004087874,0.000381113,0.0000170939,0.004340567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000740896,"threshold_uncertainty_score":0.00247848,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02454738530838382,"score_gpt":0.25422476391499,"score_spread":0.2296773786066062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}