{"id":"W2064169368","doi":"10.1016/s0008-6215(00)00049-5","title":"Synthesis of 4-deoxy-4-fluoro analogues of 2-acetamido-2-deoxy-d-glucose and 2-acetamido-2-deoxy-d-galactose and their effects on cellular glycosaminoglycan biosynthesis","year":2000,"lang":"en","type":"article","venue":"Carbohydrate Research","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"Kingston General Hospital; Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Glycosaminoglycan; Biosynthesis; Galactose; Biochemistry; Hepatocyte; N-Acetylglucosamine; Stereochemistry; Enzyme; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001789618,0.0009684884,0.001768488,0.0006526473,0.0004142721,0.0001677669,0.0009387544,0.0008257058,0.001104587],"category_scores_gemma":[0.001185407,0.0008492217,0.0004375945,0.001228949,0.001839297,0.0002579623,0.0003659571,0.001047735,0.00003689787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002041782,"about_ca_system_score_gemma":0.0002281219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004087184,"about_ca_topic_score_gemma":0.0000325761,"domain_scores_codex":[0.9939274,0.0006879807,0.001154935,0.00154835,0.001224145,0.001457152],"domain_scores_gemma":[0.9913974,0.005195412,0.000348298,0.00190228,0.0004235315,0.0007330761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007455252,0.0004231388,0.0007046619,0.00241862,0.0004194173,0.0001008603,0.0007953626,0.000009652917,0.9209426,0.00008232635,0.0000906762,0.07326715],"study_design_scores_gemma":[0.000833173,0.0002382836,0.0004222225,0.001158077,0.0001773955,0.00002264166,0.0009779262,0.000705711,0.9933283,0.0004136727,0.0009642109,0.0007583685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816826,0.004838951,0.000003435927,0.000285785,0.00005730625,0.0004339933,0.0003937484,0.0001291407,0.01217504],"genre_scores_gemma":[0.9923774,0.00593269,0.00008534232,0.00002748996,0.0002727001,0.0001821835,0.0000573109,0.0001668843,0.0008980113],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07250877,"threshold_uncertainty_score":0.9998085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02244512122458336,"score_gpt":0.2594394611903657,"score_spread":0.2369943399657823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}