{"id":"W2064182285","doi":"10.1186/1471-2407-14-801","title":"Cytosolic galectin-7 impairs p53 functions and induces chemoresistance in breast cancer cells","year":2014,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Universitaire Stichting","keywords":"Apoptosis; Cancer cell; Molecular biology; Cytosol; Galectin-3; Mutant; Biology; Cancer research; Chemistry; Cell biology; Cancer; Biochemistry; Enzyme; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001592418,0.0002100741,0.000320821,0.0001125465,0.0001617758,0.00001853249,0.0001402983,0.0002517971,0.001538836],"category_scores_gemma":[0.00001348959,0.0001863351,0.00005896038,0.0002550085,0.0002262913,0.00007352011,0.00005950784,0.0003105655,0.00006145529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001325373,"about_ca_system_score_gemma":0.0001822921,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005862487,"about_ca_topic_score_gemma":0.02502348,"domain_scores_codex":[0.9986808,0.0001328332,0.0002392777,0.0004531561,0.00002927263,0.0004646563],"domain_scores_gemma":[0.9994925,0.00008442219,0.0001114256,0.0002162676,0.00005802281,0.00003734971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003897166,0.00009213208,0.2647482,0.00007308691,0.00008587966,0.000001000935,0.0003618133,0.00007762706,0.7021698,0.0001752753,0.01751666,0.01430875],"study_design_scores_gemma":[0.002513274,0.000113034,0.8614006,0.0001162761,0.00006247589,0.00008028292,0.0003294145,0.00001918619,0.06974731,0.0001331857,0.0649907,0.0004942926],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869233,0.007835416,0.0000455827,0.0005721922,0.001369743,0.0001677669,0.0001045305,0.00005704713,0.002924423],"genre_scores_gemma":[0.9928255,0.001004581,0.0000172712,0.0004313288,0.0002060569,0.0002540922,0.00001224102,0.00002172147,0.005227192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6324226,"threshold_uncertainty_score":0.9993739,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009991402599199492,"score_gpt":0.2387332673238768,"score_spread":0.2287418647246773,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}