{"id":"W2064207737","doi":"10.1038/nature02030","title":"Basal body dysfunction is a likely cause of pleiotropic Bardet–Biedl syndrome","year":2003,"lang":"en","type":"article","venue":"Nature","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":690,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Ciliogenesis; Cilium; Basal body; Bardet–Biedl syndrome; Biology; Intraflagellar transport; Genetics; Cell biology; Polydactyly; Caenorhabditis elegans; Motile cilium; Gene; Mutant; Phenotype; Flagellum","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002427861,0.000901903,0.0007873587,0.001201994,0.0005829067,0.0006221638,0.0007626183,0.002206707,0.003628858],"category_scores_gemma":[0.001088556,0.0003996436,0.0002860566,0.0006805881,0.0009928581,0.0006330147,0.000578889,0.001275773,0.0007428865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000239212,"about_ca_system_score_gemma":0.0002855307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005133129,"about_ca_topic_score_gemma":0.0003524833,"domain_scores_codex":[0.9997929,0.00003079923,0.00002201966,0.00005235065,0.00006831427,0.00003361532],"domain_scores_gemma":[0.9994948,0.0001552168,0.0001574924,0.000033281,0.00002665406,0.0001325433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002602003,0.0001484074,0.08413807,0.0003685199,0.000159292,0.5665996,0.0004479972,0.0004772677,0.3301161,0.002824466,0.001232407,0.01088583],"study_design_scores_gemma":[0.0002732542,0.000278902,0.1671613,0.00006807844,0.0002815265,0.7596786,0.0003340452,0.002928626,0.06199496,0.003153911,0.00376753,0.0000792748],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894271,0.001898807,0.003263389,0.0009325488,0.00009379201,0.00002012556,0.0004688707,0.0002152552,0.003680015],"genre_scores_gemma":[0.998111,0.0002608695,0.0009674285,0.00008459586,0.00004955414,0.000005428401,0.0001475315,0.00001759721,0.0003560566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003628858,"threshold_uncertainty_score":0.01213974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004330836844067304,"score_gpt":0.22856045371107,"score_spread":0.2242296168670027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}