{"id":"W2064208027","doi":"10.1016/j.ydbio.2008.02.010","title":"Canonical WNT/β-catenin signaling is required for ureteric branching","year":2008,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Ureteric bud; Wnt signaling pathway; Biology; Kidney development; Morphogenesis; Phenotype; Kidney; Cell biology; Mutant; Nephron; Cancer research; Pathology; Gene; Genetics; Signal transduction; Embryonic stem cell; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000172656,0.0002588436,0.000254176,0.0004088238,0.0004054366,0.0009161452,0.0002688658,0.000344421,0.001437],"category_scores_gemma":[0.000322159,0.0004096288,0.0002196589,0.0002763188,0.0004837803,0.0004170195,0.0003709557,0.0006024707,0.0005618195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007961581,"about_ca_system_score_gemma":0.0007247377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002379094,"about_ca_topic_score_gemma":0.004677623,"domain_scores_codex":[0.9997482,0.0000209461,0.00002015059,0.00004233756,0.00009386713,0.00007452773],"domain_scores_gemma":[0.999674,0.00002869554,0.0001000719,0.00003943083,0.00004126495,0.0001165536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008608335,0.000006225007,0.0008719548,0.00002099864,0.000003263741,0.0002430308,0.00001007311,0.00004106531,0.996887,0.000590177,0.00004867728,0.001191469],"study_design_scores_gemma":[0.00002051204,0.00004704548,0.02777867,0.000007512897,0.00001998735,0.001540875,0.00007305766,0.001268765,0.9644735,0.0003410581,0.004421144,0.000007865487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834553,0.004187095,0.006419306,0.0003275112,0.00005232603,0.00002410028,0.0004631958,0.0002441205,0.004827123],"genre_scores_gemma":[0.9946791,0.0006726671,0.001511888,0.0000425164,0.000005445042,0.000007316296,0.000303961,0.00002663327,0.002750514],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002379094,"threshold_uncertainty_score":0.005776525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02148358191061486,"score_gpt":0.2572068399908028,"score_spread":0.235723258080188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}