{"id":"W2064332074","doi":"10.1038/sj.onc.1206896","title":"Interaction between the HPV E7 oncoprotein and the transcriptional coactivator p300","year":2003,"lang":"en","type":"article","venue":"Oncogene","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":141,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Transactivation; Biology; Coactivator; Immunoprecipitation; Phosphorylation; Plasma protein binding; Carcinogenesis; Binding site; DNA-binding protein; Transcription factor; Genetics; Cancer research; Cell biology; Cancer; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006441324,0.0001173028,0.0001106776,0.00002091885,0.0002021027,0.00003768949,0.0001720731,0.00008466643,0.000153147],"category_scores_gemma":[0.00006554474,0.00006826557,0.000079978,0.00008300999,0.0002242011,0.000004370649,0.00002813805,0.0001569767,0.0000175166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002294828,"about_ca_system_score_gemma":0.0001033726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002918175,"about_ca_topic_score_gemma":0.00007693999,"domain_scores_codex":[0.9989027,0.0003584917,0.0001405254,0.00022465,0.0001856514,0.0001879721],"domain_scores_gemma":[0.999487,0.00005482614,0.00004725638,0.0003008633,0.00005255986,0.00005750923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001412176,0.00003149359,0.0005389999,0.000005186838,0.0001387429,8.758749e-7,0.00007696819,0.00001221114,0.9788974,0.0003086199,0.0004277647,0.01814959],"study_design_scores_gemma":[0.001526907,0.0005031177,0.000627791,0.000003702005,0.00002127299,0.00001640131,0.00007397632,0.0000142508,0.8302286,0.0003329133,0.1665467,0.0001043061],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929075,0.002250257,0.0004476746,0.001651611,0.00009075577,0.0003878703,0.00002558974,0.000007153142,0.002231651],"genre_scores_gemma":[0.9979009,0.0003255202,0.00009040492,0.0004502349,0.000315496,0.00007600415,0.00003900618,0.0000194381,0.0007829772],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.166119,"threshold_uncertainty_score":0.2783789,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02308606330956255,"score_gpt":0.301608692777749,"score_spread":0.2785226294681865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}