{"id":"W2064382404","doi":"10.1139/y06-077","title":"Methylglyoxal, oxidative stress, and hypertension","year":2006,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Methylglyoxal; Glycation; Oxidative stress; Reactive oxygen species; Context (archaeology); Chemistry; Diabetes mellitus; Essential hypertension; Medicine; Endocrinology; Internal medicine; Biochemistry; Biology; Blood pressure; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002087939,0.000235155,0.0007368437,0.0002307674,0.0001305171,0.000008693358,0.000195775,0.0003679293,0.0001307479],"category_scores_gemma":[0.00008004794,0.0001912429,0.0001035477,0.00009974876,0.0004823704,0.000007276436,0.00005471172,0.0004795397,0.000003297693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003491371,"about_ca_system_score_gemma":0.001146912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001512593,"about_ca_topic_score_gemma":0.0002446612,"domain_scores_codex":[0.9985472,0.0004307746,0.0003574116,0.000313026,0.00004684145,0.0003047313],"domain_scores_gemma":[0.9989046,0.00009071098,0.0003362687,0.0001272732,0.0002112556,0.0003298539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001366936,0.00008895587,0.00004612183,0.009513942,0.001598713,0.0003190457,0.00007067699,0.0000442383,0.2495725,0.0002669713,0.04718117,0.691161],"study_design_scores_gemma":[0.0002717198,0.0002664156,0.00002305668,0.0001852847,0.0002551941,0.0004136579,0.000007638281,7.270019e-7,0.008024207,0.0001751794,0.9902024,0.0001745283],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003365605,0.9957249,0.00001887717,0.0001072425,0.0004317792,0.0001853049,0.0001031344,0.00000125798,0.0000619335],"genre_scores_gemma":[0.003249837,0.9951471,0.000182699,0.0001843334,0.0008315647,0.000008340339,0.0001623751,0.00002552909,0.0002081966],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9430212,"threshold_uncertainty_score":0.7798658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0381128878482185,"score_gpt":0.3582283737659037,"score_spread":0.3201154859176852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}