{"id":"W2064405608","doi":"10.1159/000110789","title":"<i>Sorl1</i> as an Alzheimer’s Disease Predisposition Gene?","year":2007,"lang":"en","type":"article","venue":"Neurodegenerative Diseases","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kronos (Canada)","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institute on Aging; National Institutes of Health; National Heart, Lung, and Blood Institute; National Alzheimer's Coordinating Center","keywords":"Apolipoprotein E; Allele; Genetics; Genetic predisposition; Alzheimer's disease; Genetic association; Biology; Disease; Genome-wide association study; Gene; Neuroscience; Single-nucleotide polymorphism; Medicine; Genotype; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000539439,0.0006463397,0.000601944,0.000686313,0.0003762641,0.001118403,0.0006963222,0.001060181,0.006509164],"category_scores_gemma":[0.001009455,0.0001978481,0.0004511773,0.0008520575,0.000642544,0.0005875469,0.0002527394,0.00045924,0.001165408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002267321,"about_ca_system_score_gemma":0.0002442468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001906637,"about_ca_topic_score_gemma":0.001719477,"domain_scores_codex":[0.9997807,0.00005230794,0.00001409475,0.00007956402,0.0000327018,0.00004065876],"domain_scores_gemma":[0.9995714,0.0001043082,0.0001402185,0.00003962166,0.00004079572,0.0001037058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009898159,0.0005795669,0.6103764,0.0007782461,0.001600954,0.0272548,0.0008811,0.001254415,0.1653381,0.005486473,0.0132334,0.1633184],"study_design_scores_gemma":[0.0009409955,0.001759251,0.8061757,0.0006632409,0.004925332,0.06545129,0.001315069,0.004647922,0.0409337,0.01089866,0.06211518,0.0001736349],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760897,0.01143917,0.001824644,0.004833667,0.0002164616,0.00002606829,0.0009966515,0.0001262169,0.004447514],"genre_scores_gemma":[0.9914985,0.002606453,0.001539254,0.001151979,0.000189944,0.00001036496,0.0005634712,0.00004501585,0.002394967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006509164,"threshold_uncertainty_score":0.02177531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02888487354309534,"score_gpt":0.321878046529441,"score_spread":0.2929931729863456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}