{"id":"W2064411248","doi":"10.1016/s0014-2999(02)02816-9","title":"Modulation of spontaneous transient Ca2+-activated K+ channel currents by cADP-ribose in vascular smooth muscle cells","year":2002,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Calcium signaling and nucleotide metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Heart and Stroke Foundation of Canada","keywords":"Ryanodine receptor; Chemistry; Endoplasmic reticulum; Vascular smooth muscle; Ribose; Biophysics; Myocyte; Endogeny; Antagonist; Endocrinology; Internal medicine; Smooth muscle; Biology; Receptor; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002260004,0.0002189499,0.000440963,0.0001779899,0.0002413658,0.0004804444,0.000389084,0.0003127389,0.0007785714],"category_scores_gemma":[0.0003722054,0.0001831733,0.0003703811,0.0002666942,0.0003305773,0.0004495873,0.0002281579,0.00079841,0.0002022387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005333442,"about_ca_system_score_gemma":0.0002266385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001154443,"about_ca_topic_score_gemma":0.001884277,"domain_scores_codex":[0.9997714,0.00005066589,0.00002655499,0.0000315745,0.00003582345,0.00008390399],"domain_scores_gemma":[0.9997682,0.00008146261,0.00002772755,0.00005973145,0.00002276026,0.00004010845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004847685,0.00003439623,0.0001091948,0.00002927464,0.000005634836,0.00007976509,0.00003366725,0.00007224383,0.998137,0.0002046935,0.00003210169,0.0007773961],"study_design_scores_gemma":[0.00007633495,0.0004845696,0.007808932,0.000005682914,0.00002133251,0.0001210013,0.00006419128,0.001846245,0.9886481,0.00008247498,0.000831463,0.000009568345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973459,0.0009250258,0.0008120029,0.0001019766,0.00002363278,0.000007812754,0.0002147291,0.00004476599,0.0005241215],"genre_scores_gemma":[0.9981614,0.000421416,0.0005711585,0.00002919623,0.00001465368,0.00001889489,0.0002501447,0.00001419398,0.0005189763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001154443,"threshold_uncertainty_score":0.003869712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01417263919649559,"score_gpt":0.2424428869537661,"score_spread":0.2282702477572706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}