{"id":"W2064431299","doi":"10.1016/j.ygeno.2004.03.008","title":"The KCNQ1OT1 promoter, a key regulator of genomic imprinting in human chromosome 11p15.5","year":2004,"lang":"en","type":"article","venue":"Genomics","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Genomic imprinting; Regulator; Imprinting (psychology); Genetics; Key (lock); Chromosome; Gene; Computational biology; DNA methylation; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001355607,0.0003578598,0.0002340175,0.0003376892,0.0002291774,0.000295608,0.0003130716,0.0002795151,0.001469332],"category_scores_gemma":[0.0004001979,0.0001602916,0.000142009,0.0001928355,0.0004784972,0.0001582823,0.0003281635,0.0003487964,0.0005360263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006070099,"about_ca_system_score_gemma":0.0004565011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003399802,"about_ca_topic_score_gemma":0.00428766,"domain_scores_codex":[0.9998567,0.00001223439,0.000008171894,0.00005445413,0.00004247421,0.00002594196],"domain_scores_gemma":[0.9997706,0.00005146691,0.00006930301,0.00001161837,0.0000300154,0.00006703645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006796247,0.00001602758,0.009463222,0.0002286443,0.00001587509,0.001581101,0.0001580948,0.0007027395,0.9712828,0.001498182,0.0006556535,0.01371809],"study_design_scores_gemma":[0.0001789072,0.0003324039,0.191201,0.0001601232,0.00008949974,0.01051949,0.0003118326,0.003431641,0.7615293,0.002469566,0.02972789,0.00004832534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9756605,0.005668201,0.01168694,0.0006177824,0.0002021814,0.00005276375,0.002162221,0.0002322296,0.003717332],"genre_scores_gemma":[0.9929048,0.0006760739,0.002352044,0.0001245244,0.00002559865,0.00001962648,0.001393909,0.00003646949,0.002466984],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003399802,"threshold_uncertainty_score":0.006760001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007689216356127349,"score_gpt":0.2260845621412258,"score_spread":0.2183953457850984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}