{"id":"W2064431299","doi":"10.1016/j.ygeno.2004.03.008","title":"The KCNQ1OT1 promoter, a key regulator of genomic imprinting in human chromosome 11p15.5","year":2004,"lang":"en","type":"article","venue":"Genomics","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Genomic imprinting; Regulator; Imprinting (psychology); Genetics; Key (lock); Chromosome; Gene; Computational biology; DNA methylation; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003303233,0.0001497818,0.0001669677,0.00003961764,0.0001302965,0.00003106064,0.0003539423,0.0001143807,0.000005781378],"category_scores_gemma":[0.00003444736,0.0001308502,0.00009880211,0.00006763122,0.00009797674,0.000002336472,0.0002909089,0.000100126,0.000007872829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005790619,"about_ca_system_score_gemma":0.0001210595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008197821,"about_ca_topic_score_gemma":0.00009211879,"domain_scores_codex":[0.9988284,0.00002708536,0.0004049969,0.0003042695,0.00008327568,0.0003519915],"domain_scores_gemma":[0.9992298,0.000006532567,0.0001690114,0.0005002129,0.00004120044,0.00005316559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000004867004,0.00003123536,0.002615163,0.00001710542,0.0000236418,0.0000010473,0.0001863924,0.0005897353,0.9936556,0.0003115721,0.000006747436,0.002556944],"study_design_scores_gemma":[0.001636749,0.0003358075,0.1252774,0.00003888865,0.00001676725,0.00007943443,0.0003045507,0.00007723486,0.8606884,0.001681072,0.009506341,0.0003573143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982747,0.0006314861,0.000206519,0.0001010007,0.0001227363,0.0002524423,0.000004180272,0.000006613969,0.0004003477],"genre_scores_gemma":[0.9975923,0.0001496864,0.001888573,0.00003758612,0.0001417462,0.00001348322,0.00001234321,0.00003204154,0.0001322083],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1329671,"threshold_uncertainty_score":0.5335915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007689216356127349,"score_gpt":0.2260845621412258,"score_spread":0.2183953457850984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}