{"id":"W2064465745","doi":"10.1007/s00109-014-1162-1","title":"Activation of the EGFR/p38/JNK pathway by mitochondrial-derived hydrogen peroxide contributes to oxygen-induced contraction of ductus arteriosus","year":2014,"lang":"en","type":"article","venue":"Journal of Molecular Medicine","topic":"Cardiovascular Conditions and Treatments","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Ductus arteriosus; Contraction (grammar); Hydrogen peroxide; p38 mitogen-activated protein kinases; Reactive oxygen species; Mitochondrion; Oxygen; Chemistry; Internal medicine; Medicine; Cardiology; Cell biology; Biochemistry; Biology; Kinase; Protein kinase A","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002026024,0.0002943262,0.0002328067,0.0002222762,0.0002787059,0.0002115692,0.0001993923,0.0002879641,0.002007636],"category_scores_gemma":[0.0001746014,0.0001507189,0.000421862,0.00009017422,0.0001948768,0.0003888786,0.000330774,0.000808173,0.0002865815],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000231785,"about_ca_system_score_gemma":0.0002703191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000431003,"about_ca_topic_score_gemma":0.0004958213,"domain_scores_codex":[0.9998556,0.00002136835,0.000009583661,0.00001682973,0.00003052902,0.00006613168],"domain_scores_gemma":[0.9999148,0.000007975583,0.00001999942,0.00001147265,0.00001351323,0.00003228944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009575112,0.0002159173,0.0007109139,0.0001194126,0.00001702067,0.0003640804,0.00005510222,0.00008269371,0.9921449,0.000503278,0.0002302555,0.004598954],"study_design_scores_gemma":[0.0001579554,0.001149213,0.05831024,0.00002349193,0.00007698551,0.001415696,0.0002774256,0.004085573,0.9293456,0.0006836972,0.004459114,0.0000150055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950464,0.001318752,0.001545573,0.0002895822,0.00006101791,0.00003497457,0.00009048014,0.00002993469,0.001583381],"genre_scores_gemma":[0.9967334,0.0007460696,0.0004735049,0.00004132666,0.00003143835,0.00002527034,0.0001232466,0.000004211064,0.001821488],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002007636,"threshold_uncertainty_score":0.006716192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007178442039911605,"score_gpt":0.2343394981998391,"score_spread":0.2271610561599275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}