{"id":"W2064508141","doi":"10.1097/jto.0000000000000058","title":"NCIC CTG IND.190 Phase I Trial of Dalotuzumab (MK-0646) in Combination with Cisplatin and Etoposide in Extensive-Stage Small-Cell Lung Cancer","year":2014,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; Queen's University; McMaster University; University of Ottawa; Ottawa Hospital; Princess Margaret Cancer Centre; Juravinski Cancer Centre","funders":"","keywords":"Medicine; Neutropenia; Leukopenia; Etoposide; Internal medicine; Gastroenterology; Cancer; Anemia; Surgery; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001351152,0.001721389,0.002456558,0.0005693007,0.0004741982,0.001453937,0.001452392,0.001264588,0.006216129],"category_scores_gemma":[0.0007399328,0.00074379,0.001651413,0.0006344425,0.001154501,0.00102181,0.0005273729,0.004262545,0.001906058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001650927,"about_ca_system_score_gemma":0.002225906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003318305,"about_ca_topic_score_gemma":0.01175518,"domain_scores_codex":[0.9996223,0.0001605895,0.00001604535,0.00005893121,0.00003348331,0.0001085191],"domain_scores_gemma":[0.9994828,0.00006769523,0.00007487764,0.00004315019,0.00002181871,0.0003097908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7361594,0.04053741,0.004656423,0.001345897,0.001938007,0.0002654865,0.000320314,0.006735272,0.03176577,0.001107278,0.0192908,0.1558779],"study_design_scores_gemma":[0.7196175,0.2580394,0.008793839,0.00007176627,0.0006642459,0.0003640984,0.00007721751,0.001963058,0.003220368,0.0004059544,0.006734142,0.00004847935],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9766054,0.00560094,0.0008903747,0.001665091,0.0005458752,0.002798184,0.004194134,0.000414708,0.007285217],"genre_scores_gemma":[0.9730854,0.005043762,0.00228569,0.001607194,0.0002623299,0.001972421,0.006786952,0.0001018361,0.008854416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006216129,"threshold_uncertainty_score":0.02079505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03256486841170175,"score_gpt":0.4600659020599597,"score_spread":0.427501033648258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}