{"id":"W2064549315","doi":"10.1159/000340056","title":"Randomized, Double-Blind, Parallel-Group, 48-Week Study for Efficacy and Safety of a Higher-Dose Rivastigmine Patch (15 vs. 10 cm<sup>2</sup>) in Alzheimers Disease","year":2012,"lang":"en","type":"article","venue":"Dementia and Geriatric Cognitive Disorders","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Cilag; Novartis Pharma; Allergan; H. Lundbeck A/S; Merz Pharmaceuticals; Novo Nordisk; Eisai; Sanofi; GlaxoSmithKline; Pfizer; Novartis Pharmaceuticals Corporation; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Rivastigmine; Tolerability; Medicine; Dementia; Activities of daily living; Randomized controlled trial; Alzheimer's disease; Cognitive decline; Internal medicine; Adverse effect; Donepezil; Disease; Physical therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002543431,0.001744935,0.004662701,0.0005491399,0.0004647308,0.001133102,0.00134012,0.002185975,0.007098297],"category_scores_gemma":[0.002621713,0.0008587848,0.001428721,0.0004918824,0.00197884,0.001521045,0.0004750227,0.003364605,0.001427796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008174459,"about_ca_system_score_gemma":0.0009059246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005108623,"about_ca_topic_score_gemma":0.0009761117,"domain_scores_codex":[0.9987441,0.0006337916,0.0001065769,0.000266288,0.00009353171,0.000155615],"domain_scores_gemma":[0.9978096,0.0007161708,0.0005077372,0.0002840754,0.0001421172,0.0005402516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9832686,0.008295814,0.0002275639,0.0001503839,0.0002215369,0.0000118926,0.00002369453,0.00009309859,0.002522359,0.00002527039,0.0001741166,0.004985793],"study_design_scores_gemma":[0.9217019,0.07639679,0.0009647296,0.000006575628,0.0001104596,0.00001524907,0.000008725186,0.0001751586,0.0004190948,0.00004129542,0.0001525386,0.000007596755],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939102,0.001036907,0.0005508045,0.0002342409,0.000380815,0.002557144,0.0005083035,0.0001115938,0.0007099501],"genre_scores_gemma":[0.9884884,0.0007839151,0.002133929,0.0006250626,0.000630316,0.004598395,0.00065311,0.00003590605,0.002050995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007098297,"threshold_uncertainty_score":0.02374613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02669365877260926,"score_gpt":0.3220197765321212,"score_spread":0.2953261177595119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}