{"id":"W2064555218","doi":"10.3109/00498250903330348","title":"Characterization of the porcine constitutive androstane receptor (CAR) and its splice variants","year":2009,"lang":"en","type":"article","venue":"Xenobiotica","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; University of Texas Southwestern Medical Center","keywords":"Constitutive androstane receptor; Agonist; Pregnane X receptor; Chemistry; Androgen receptor; Dihydrotestosterone; Receptor; Luciferase; CYP3A4; Farnesoid X receptor; Inverse agonist; Molecular biology; Pharmacology; Biology; Internal medicine; Nuclear receptor; Androgen; Biochemistry; Cytochrome P450; Gene; Transcription factor; Medicine; Enzyme; Prostate cancer; Transfection","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008127397,0.00008173633,0.0002021443,0.00002363682,0.00007846986,0.000002527315,0.0000331585,0.00004028248,0.00002866258],"category_scores_gemma":[0.0001462731,0.00004646515,0.00002725445,0.0001452882,0.0001427319,0.00003847568,0.00002837042,0.00008448315,0.00000773445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001236155,"about_ca_system_score_gemma":0.00003640618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003130186,"about_ca_topic_score_gemma":5.826672e-7,"domain_scores_codex":[0.9994592,0.00001957185,0.0001353274,0.0001724861,0.0001121394,0.0001012529],"domain_scores_gemma":[0.9995961,0.00001506811,0.00005757937,0.0001296069,0.0001605001,0.0000411674],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001170715,0.00008399473,0.002656593,0.00002840785,0.00004061494,0.000003087563,0.0003744261,6.834635e-8,0.9929277,0.003028398,0.00003907958,0.0007006022],"study_design_scores_gemma":[0.0004919842,0.0002779159,0.7052947,0.0001113855,0.00008014576,0.00004021045,0.0001149737,0.000007720304,0.2924917,0.00006107041,0.0009655335,0.0000626181],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865786,0.0003885212,0.00001062331,0.006554687,0.0001199973,0.0003261449,0.00003712854,0.00001408373,0.005970144],"genre_scores_gemma":[0.9985372,0.0002765776,0.00004041965,0.0002821928,0.0001260151,8.253377e-7,0.000009827411,0.000003761548,0.0007232071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7026381,"threshold_uncertainty_score":0.1894794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01201777377850522,"score_gpt":0.2379280710175601,"score_spread":0.2259102972390549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}