{"id":"W2064555218","doi":"10.3109/00498250903330348","title":"Characterization of the porcine constitutive androstane receptor (CAR) and its splice variants","year":2009,"lang":"en","type":"article","venue":"Xenobiotica","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; University of Texas Southwestern Medical Center","keywords":"Constitutive androstane receptor; Agonist; Pregnane X receptor; Chemistry; Androgen receptor; Dihydrotestosterone; Receptor; Luciferase; CYP3A4; Farnesoid X receptor; Inverse agonist; Molecular biology; Pharmacology; Biology; Internal medicine; Nuclear receptor; Androgen; Biochemistry; Cytochrome P450; Gene; Transcription factor; Medicine; Enzyme; Prostate cancer; Transfection","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002092449,0.000205457,0.0002295977,0.0002519106,0.0001202352,0.0003624854,0.0002328808,0.0002624464,0.001458641],"category_scores_gemma":[0.0002625115,0.0001643378,0.000542498,0.0002213174,0.0001764409,0.0001884412,0.0001459886,0.0004367156,0.0009850538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002232094,"about_ca_system_score_gemma":0.0001818337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007903923,"about_ca_topic_score_gemma":0.0009155339,"domain_scores_codex":[0.9998196,0.00002675726,0.00001610821,0.00004966373,0.0000524482,0.0000354999],"domain_scores_gemma":[0.9997875,0.00004675455,0.00003774228,0.00003622672,0.00004730811,0.00004446288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001198964,0.00001772673,0.00118803,0.00002891573,0.000007991853,0.0001777098,0.00002280579,0.00004337454,0.9964352,0.0001064922,0.00005145812,0.001800429],"study_design_scores_gemma":[0.00009869826,0.002804978,0.1233692,0.00004268504,0.0002084955,0.01540587,0.00035309,0.003850433,0.8128243,0.0002653573,0.04072645,0.00005034671],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884615,0.002582937,0.004855444,0.0001617508,0.00004867816,0.00005141703,0.001258333,0.00004583215,0.002534141],"genre_scores_gemma":[0.9702433,0.001981526,0.008271117,0.0002406902,0.00007594478,0.00005459622,0.01395917,0.0000680675,0.005105504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001458641,"threshold_uncertainty_score":0.004879653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01201777377850522,"score_gpt":0.2379280710175601,"score_spread":0.2259102972390549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}