{"id":"W2064562633","doi":"10.1095/biolreprod.107.060681","title":"Modulation of Human Arterial Tone During Pregnancy: The Effect of the Bioactive Metabolite Sphingosine-1-Phosphate1","year":2007,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Biology; Endocrinology; Rho-associated protein kinase; Myograph; Vasoconstriction; Internal medicine; Cerebral arteries; Vasodilation; Sphingosine-1-phosphate; Receptor; Sphingosine-1-phosphate receptor; Contraction (grammar); Artery; Nitric oxide synthase; Nitric oxide; Sphingosine; Signal transduction; Medicine; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007056684,0.0001169567,0.0002338781,0.00004469866,0.00009639226,0.00000231268,0.0001633138,0.0001307916,0.000003674698],"category_scores_gemma":[0.0002208501,0.00007014033,0.0001351284,0.0001480155,0.0002938637,0.00000674423,0.00007425567,0.00006885656,1.907099e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005887215,"about_ca_system_score_gemma":0.00001387871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009383554,"about_ca_topic_score_gemma":0.000005977259,"domain_scores_codex":[0.9989437,0.000152208,0.0003582711,0.0003157584,0.00008594393,0.0001440634],"domain_scores_gemma":[0.9988497,0.00001915964,0.0004444362,0.0005606972,0.0001108524,0.00001514662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000316243,0.00002271567,0.01336884,0.00004541322,0.00007731868,6.480778e-8,0.0001268171,0.00007225823,0.9820375,0.0001413698,0.000002922776,0.003788546],"study_design_scores_gemma":[0.0005009944,0.0001906395,0.141392,0.00002487341,0.0000484139,0.000006407256,0.00002800663,0.000003797307,0.8574015,0.00006008428,0.0002871565,0.00005608648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931273,0.005260206,0.000333303,0.00003789756,0.0008508369,0.0003236294,0.000008830036,0.000005932019,0.00005199828],"genre_scores_gemma":[0.9991217,0.0001195551,0.00008082618,0.000002335957,0.0005777566,0.000007026962,0.0000269857,0.00001001638,0.00005380074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1280232,"threshold_uncertainty_score":0.2860239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007325565489389521,"score_gpt":0.2706370153645141,"score_spread":0.2633114498751246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}