{"id":"W2064585559","doi":"10.1038/mtna.2014.16","title":"DNA Ministrings: Highly Safe and Effective Gene Delivery Vectors","year":2014,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Plasmid; Biology; DNA; Transfection; Gene; In vitro recombination; Gene delivery; Molecular biology; Cell biology; Genetics; Gene expression; Molecular cloning","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004706567,0.0003750178,0.0003001372,0.0001096602,0.0001781083,0.00007448842,0.000403678,0.000269704,0.00004872],"category_scores_gemma":[0.00006248269,0.0003615803,0.0001748257,0.0001803103,0.0002526634,0.000007919275,0.0001704783,0.000194684,0.00005185912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003682333,"about_ca_system_score_gemma":0.00006163572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001641455,"about_ca_topic_score_gemma":0.00001041147,"domain_scores_codex":[0.9977623,0.0003880973,0.0002468252,0.0007363762,0.0003283281,0.0005380817],"domain_scores_gemma":[0.9987768,0.00003737713,0.0000861787,0.0007547706,0.000118884,0.0002260127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00171305,0.00008646608,0.000584105,0.00001406633,0.0002095354,0.00001538777,0.00006635171,0.00002686997,0.9519356,0.00004489692,0.0001709562,0.04513268],"study_design_scores_gemma":[0.002084081,0.004373838,0.002691947,0.00001403041,0.00001552296,0.00002150224,0.00001684661,0.0000678476,0.9639306,0.0001192952,0.02624929,0.0004151916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945018,0.00266844,0.001211278,0.000205025,0.0001205187,0.0005395844,0.00001603123,0.00004578084,0.0006915706],"genre_scores_gemma":[0.9964337,0.0008968495,0.0005120462,0.001481116,0.0002203922,0.00008348822,0.0000793238,0.000106931,0.0001862072],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04471749,"threshold_uncertainty_score":0.9998836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006408798544861105,"score_gpt":0.2415381393006253,"score_spread":0.2351293407557642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}