{"id":"W2064585559","doi":"10.1038/mtna.2014.16","title":"DNA Ministrings: Highly Safe and Effective Gene Delivery Vectors","year":2014,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Plasmid; Biology; DNA; Transfection; Gene; In vitro recombination; Gene delivery; Molecular biology; Cell biology; Genetics; Gene expression; Molecular cloning","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004610274,0.0008802216,0.0004568001,0.000860152,0.0002644591,0.0006238159,0.0006158706,0.0005553854,0.002220386],"category_scores_gemma":[0.0003739683,0.0004728993,0.0003085295,0.0005323478,0.0003927374,0.0005502596,0.0004776467,0.0009364515,0.002105973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003176629,"about_ca_system_score_gemma":0.0003581646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002049395,"about_ca_topic_score_gemma":0.0002918569,"domain_scores_codex":[0.9994383,0.0001111637,0.00005356264,0.00009297008,0.000260575,0.00004332442],"domain_scores_gemma":[0.9998028,0.00003109838,0.00007521657,0.00002076549,0.00003445327,0.00003577995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001393073,0.00003675123,0.0001212292,0.0002062028,0.00001129709,0.00009032369,0.00003813608,0.0001412427,0.9823779,0.001508497,0.0007159018,0.01461315],"study_design_scores_gemma":[0.00002907124,0.0003045941,0.0004567821,0.00002568206,0.00002707072,0.0007384726,0.00001591395,0.000770434,0.9591239,0.0003772343,0.03811442,0.00001648372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4186815,0.02394514,0.5261682,0.0008055271,0.0007407062,0.001530565,0.004789559,0.005694482,0.01764432],"genre_scores_gemma":[0.6079426,0.02025143,0.3033692,0.0005119739,0.000241942,0.001377018,0.01154093,0.000872716,0.05389224],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002220386,"threshold_uncertainty_score":0.007427931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006408798544861105,"score_gpt":0.2415381393006253,"score_spread":0.2351293407557642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}