{"id":"W2064656560","doi":"10.1593/neo.07544","title":"PEGylated DX-1000: Pharmacokinetics and Antineoplastic Activity of a Specific Plasmin Inhibitor","year":2007,"lang":"en","type":"article","venue":"Neoplasia","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Pharmacokinetics; Pharmacology; Medicine; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001089586,0.0002265406,0.0001721869,0.0001244021,0.00004109419,0.0002374378,0.0001629895,0.0002282796,0.0006195558],"category_scores_gemma":[0.0002250382,0.00008519607,0.00007817325,0.0001063792,0.0001475689,0.0002599469,0.00006823182,0.0003026085,0.0001546868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000305832,"about_ca_system_score_gemma":0.000150401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006228642,"about_ca_topic_score_gemma":0.0003162322,"domain_scores_codex":[0.9999511,0.00001088737,0.00000309795,0.00001232282,0.00001367333,0.000008807649],"domain_scores_gemma":[0.9999565,0.00001013396,0.0000132336,0.000004779938,0.00000297142,0.00001236364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001112519,0.0001619966,0.0004563302,0.0000301072,0.000008875566,0.00005182019,0.00001361419,0.0004700869,0.9875426,0.0001075742,0.00008662844,0.009957872],"study_design_scores_gemma":[0.0001363558,0.002965111,0.005802826,0.000004590208,0.00003654097,0.0005939761,0.000008521124,0.006264733,0.9813141,0.00006187984,0.002803192,0.000008209101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954942,0.001596377,0.002138508,0.00004622194,0.00001091546,0.0000230851,0.0001083754,0.00005460093,0.0005275681],"genre_scores_gemma":[0.9967687,0.0006992996,0.001181601,0.00002141884,0.000006620154,0.00001506265,0.0001786642,0.00001302217,0.001115531],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006228642,"threshold_uncertainty_score":0.002218962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007562601031297152,"score_gpt":0.2388046526322886,"score_spread":0.2312420516009914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}