{"id":"W2064656560","doi":"10.1593/neo.07544","title":"PEGylated DX-1000: Pharmacokinetics and Antineoplastic Activity of a Specific Plasmin Inhibitor","year":2007,"lang":"en","type":"article","venue":"Neoplasia","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Pharmacokinetics; Pharmacology; Medicine; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002193428,0.0001983093,0.0001959141,0.00007945844,0.00005644386,0.00001440064,0.0001067689,0.0001926857,0.00003535302],"category_scores_gemma":[0.00003571728,0.0001961657,0.00006502974,0.0001329225,0.00009083091,0.000006763127,0.0001063076,0.0001397115,0.00001086873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000935945,"about_ca_system_score_gemma":0.00004557077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008451656,"about_ca_topic_score_gemma":0.00001259446,"domain_scores_codex":[0.9988846,0.00003286565,0.0002469135,0.0003508968,0.0001754744,0.0003092911],"domain_scores_gemma":[0.9993947,0.00003181115,0.0001258459,0.00023156,0.00007832608,0.000137782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004010454,0.00009908091,0.0008546941,0.00003398737,0.00002933035,0.00001701591,0.0000352678,0.00000432795,0.9924834,0.00007486752,0.001251936,0.004715015],"study_design_scores_gemma":[0.001042164,0.0004184695,0.002556698,0.00002725,0.0000216757,0.00006341479,0.00002053146,0.00006859484,0.9822557,0.00002260875,0.01330522,0.0001977029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939314,0.0005246566,0.003382853,0.00003074316,0.0003330201,0.0002175087,0.00002901157,0.00002011334,0.001530672],"genre_scores_gemma":[0.9983717,0.0002058252,0.0006857347,0.00005114568,0.0003910871,0.000004740646,0.0000267947,0.00002787885,0.0002351141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01205328,"threshold_uncertainty_score":0.7999406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007562601031297152,"score_gpt":0.2388046526322886,"score_spread":0.2312420516009914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}