{"id":"W2064681832","doi":"10.1158/0008-5472.sabcs12-p2-14-01","title":"Abstract P2-14-01: Fulvestrant vs exemestane for treatment of metastatic breast cancer in patients with acquired resistance to non-steroidal aromatase inhibitors – a meta-analysis of EFECT and SoFEA (CRUKE/03/021 &amp; CRUK/09/007)","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Exemestane; Medicine; Fulvestrant; Internal medicine; Anastrozole; Breast cancer; Aromatase; Placebo; Oncology; Aromatase inhibitor; Tamoxifen; Metastatic breast cancer; Cancer; Gastroenterology; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.007789888,0.002031291,0.008735172,0.001411186,0.0003837878,0.002550235,0.001319006,0.002136801,0.005519692],"category_scores_gemma":[0.008633809,0.0009292472,0.03458483,0.001555281,0.0006535984,0.001240036,0.0009645062,0.003523403,0.000544592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001204222,"about_ca_system_score_gemma":0.0008441432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002821636,"about_ca_topic_score_gemma":0.005647671,"domain_scores_codex":[0.9957004,0.002702688,0.0005030959,0.0005740762,0.000324992,0.000194933],"domain_scores_gemma":[0.9950969,0.002833376,0.001120202,0.0002995244,0.0003147211,0.000335374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.09804845,0.0001056856,0.008543948,0.02392829,0.8566256,0.0001095546,0.00004028538,0.0008397689,0.001122613,0.0001139364,0.0008460293,0.009675876],"study_design_scores_gemma":[0.0227423,0.003276607,0.0123712,0.001388887,0.9568393,0.0001071639,0.0000524259,0.0007509521,0.0003202973,0.0003324371,0.001785464,0.00003296291],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2722612,0.7136754,0.002249429,0.002348987,0.002262443,0.0007396689,0.00373717,0.0002299825,0.002495814],"genre_scores_gemma":[0.9582772,0.03562963,0.0008467611,0.001608166,0.0006765767,0.0002469308,0.001413331,0.00005110839,0.001250318],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9912648,"threshold_uncertainty_score":0.04119742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04533935526388984,"score_gpt":0.3590126538527599,"score_spread":0.3136732985888701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}