{"id":"W2064697479","doi":"10.4161/cc.20801","title":"Human pluripotency: A difficult state to make smart choices","year":2012,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Biology; Cell biology; Stem cell; Computational biology; Induced pluripotent stem cell; State (computer science); Cell; Embryonic stem cell; Genetics; Computer science; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002329977,0.000509267,0.0003886432,0.0001534381,0.0001925925,0.0001058584,0.0008957293,0.000808787,0.0002171167],"category_scores_gemma":[0.00002824373,0.0004847565,0.0002205937,0.0001702108,0.00009982596,0.000004315882,0.0006331631,0.0009589367,0.001203297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005922565,"about_ca_system_score_gemma":0.0001021148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001261305,"about_ca_topic_score_gemma":0.0001154178,"domain_scores_codex":[0.9967778,0.0001633999,0.000375674,0.0009248847,0.0005640858,0.001194121],"domain_scores_gemma":[0.9982563,0.00001624206,0.0001541643,0.001110493,0.0001658474,0.0002969939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000110919,0.00006369754,0.0001598207,0.0002171809,0.00004910326,0.00006981238,0.00003680881,0.00001723855,0.3510504,2.564131e-7,0.6479265,0.0003981178],"study_design_scores_gemma":[0.0003372126,0.0001682358,0.0009826857,0.00003673138,0.00003081211,0.00001044069,0.000006050817,0.000002706181,0.09372601,0.00001312501,0.9041137,0.0005723081],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.7897174,0.006250789,0.0002014426,0.1191531,0.002032751,0.002983323,0.0008319807,0.0002020528,0.07862712],"genre_scores_gemma":[0.1683355,0.0004126744,0.0005607465,0.3155812,0.01172472,0.0004088143,0.005331744,0.0005153891,0.4971292],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.621382,"threshold_uncertainty_score":0.9997604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01298971646182832,"score_gpt":0.2580876083387456,"score_spread":0.2450978918769172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}