{"id":"W2064739762","doi":"10.1016/j.neuron.2013.01.018","title":"NLF-1 Delivers a Sodium Leak Channel to Regulate Neuronal Excitability and Modulate Rhythmic Locomotion","year":2013,"lang":"en","type":"article","venue":"Neuron","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":121,"is_retracted":false,"has_abstract":false,"ca_institutions":"Occupational Cancer Research Centre; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Rhythm; Neuroscience; Sodium channel; Leak; Psychology; Chemistry; Medicine; Sodium; Internal medicine; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008743354,0.0001491104,0.00009990959,0.00005728462,0.00009692108,0.00003801433,0.00006563598,0.0001064833,0.00006005421],"category_scores_gemma":[0.00004112907,0.0001492568,0.00005149049,0.00008067022,0.00004782612,0.00001427622,0.00009001012,0.00007585154,0.0001048535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001435644,"about_ca_system_score_gemma":0.00001398242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003268219,"about_ca_topic_score_gemma":0.00001641884,"domain_scores_codex":[0.9989973,0.00006837618,0.0001599608,0.0004338996,0.0001223389,0.0002181818],"domain_scores_gemma":[0.9994605,0.00000624926,0.00004753162,0.0002462885,0.0001016341,0.0001377565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002400203,0.0000840907,0.0007832522,0.0000386282,0.00001771182,0.0000021147,0.0001223963,0.00597192,0.9763213,0.00007373802,0.004898858,0.01144594],"study_design_scores_gemma":[0.002115424,0.00180348,0.8131716,0.00002467004,0.00003003145,0.00009664437,0.0001087965,0.05285694,0.08878705,0.0009786487,0.03921837,0.0008083951],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949008,0.00002597769,0.002402478,0.001390704,0.0004919173,0.000413908,0.000004761135,0.00003210962,0.0003373837],"genre_scores_gemma":[0.9972665,0.000026528,0.00008213349,0.0007761843,0.0003245566,0.00003753389,0.00004553947,0.00002161873,0.001419397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8875343,"threshold_uncertainty_score":0.6086516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01030846469635843,"score_gpt":0.2117974795022846,"score_spread":0.2014890148059262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}