{"id":"W2064739762","doi":"10.1016/j.neuron.2013.01.018","title":"NLF-1 Delivers a Sodium Leak Channel to Regulate Neuronal Excitability and Modulate Rhythmic Locomotion","year":2013,"lang":"en","type":"article","venue":"Neuron","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":121,"is_retracted":false,"has_abstract":false,"ca_institutions":"Occupational Cancer Research Centre; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Rhythm; Neuroscience; Sodium channel; Leak; Psychology; Chemistry; Medicine; Sodium; Internal medicine; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003532506,0.0002284688,0.0003184616,0.0002083152,0.0004379368,0.0007168674,0.0004780053,0.000694278,0.001312085],"category_scores_gemma":[0.0004170398,0.0001784516,0.0003109803,0.0001359199,0.0004773212,0.001039263,0.0004917633,0.0009532534,0.0004708383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001210814,"about_ca_system_score_gemma":0.000388312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007386678,"about_ca_topic_score_gemma":0.001327537,"domain_scores_codex":[0.999832,0.00001409574,0.00001398479,0.00004164661,0.00004568422,0.00005258944],"domain_scores_gemma":[0.9998428,0.00002518349,0.00003541365,0.00002074305,0.00002994466,0.00004597922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001187741,0.00001545502,0.0002518304,0.00001723665,0.000002663748,0.00005113186,0.00002106926,0.0001052405,0.997726,0.000459697,0.000085354,0.001145548],"study_design_scores_gemma":[0.0000465886,0.0001076239,0.003777084,0.00001077653,0.00001290063,0.0002404321,0.00009122265,0.007358481,0.9852843,0.0005526764,0.00250516,0.000012749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813694,0.0008903379,0.01437147,0.0009524478,0.0001301171,0.00002993378,0.0002937608,0.000270967,0.001691672],"genre_scores_gemma":[0.9926286,0.000354621,0.003902137,0.0001918508,0.00002628375,0.00002043129,0.0002413934,0.00008081102,0.002553848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001312085,"threshold_uncertainty_score":0.008785069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01030846469635843,"score_gpt":0.2117974795022846,"score_spread":0.2014890148059262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}